This chapter contains sections titled: Recommended Targets for Glycaemic Control Pros and
Cons of Existing Non‐Insulin Antidiabetes Therapies Why are New Drugs Needed for the …

Diabetes Mellitus is a disorder of altered glucose and lipid metabolism having
hyperglycemia as a characteristic feature. Long term uncontrolled Diabetes Mellitus …

Despite a rapid increase in the number of drugs available to treat hyperglycemia there
remain several unmet needs in the prevention and treatment of diabetes. There have also …

Diabetes mellitus is a disease with significant and rising prevalence in today's world with
high mortality, morbidity, and cost of care associated with it. In this thesis I try to cover the …

Concurrent with the spread of the western lifestyle, the prevalence of all types of diabetes is
on the rise in the worlds population. The number of diabetics is increasing by 4-5 percent …

Most of the excess mortality and much morbidity in diabetes (and in impaired glucose
tolerance) is caused by cardiovascular disease; type 2 diabetes may be regarded as a …

■ ABSTRACT The pathophysiology of type 2 diabetes mellitus involves several biologic
mechanisms and no single medication addresses them all. Most patients require more than …

Abstract The Diabetes UK Annual Professional Conference took place on March 14-16,
2007, in Glasgow, UK The meeting was devoted to basic science, clinical science and …

Until the discovery of insulin in 1921 there were no effective treatments for diabetes mellitus.
After the advent of long-acting insulin, the first oral agents, sulfonylureas became available …

As the number of individuals with diabetes, especially type 2 diabetes, continues to rise, and
the importance of achieving glycaemic targets is ever more apparent, we are treating more …