[图书][B] Next generation sequencing technologies and challenges in sequence assembly

S El-Metwally, OM Ouda, M Helmy - 2014 - books.google.com
The introduction of Next Generation Sequencing (NGS) technologies resulted in a major
transformation in the way scientists extract genetic information from biological systems …

ARAMIS: From systematic errors of NGS long reads to accurate assemblies

E Sacristán-Horcajada… - Briefings in …, 2021 - academic.oup.com
NGS long-reads sequencing technologies (or third generation) such as Pacific BioSciences
(PacBio) have revolutionized the sequencing field over the last decade improving multiple …

Bioinformatics challenges of new sequencing technology

M Pop, SL Salzberg - Trends in genetics, 2008 - cell.com
New DNA sequencing technologies can sequence up to one billion bases in a single day at
low cost, putting large-scale sequencing within the reach of many scientists. Many …

[HTML][HTML] Long walk to genomics: History and current approaches to genome sequencing and assembly

AM Giani, GR Gallo, L Gianfranceschi… - Computational and …, 2020 - Elsevier
Genomes represent the starting point of genetic studies. Since the discovery of DNA
structure, scientists have devoted great efforts to determine their sequence in an exact way …

Sequence assembly using next generation sequencing data—challenges and solutions

FYL Chin, HCM Leung, SM Yiu - Science China Life Sciences, 2014 - Springer
Sequence assembling is an important step for bioinformatics study. With the help of next
generation sequencing (NGS) technology, high throughput DNA fragment (reads) can be …

Current challenges and solutions of de novo assembly

X Liao, M Li, Y Zou, FX Wu, J Wang - Quantitative Biology, 2019 - Wiley Online Library
Background Next‐generation sequencing (NGS) technologies have fostered an
unprecedented proliferation of high‐throughput sequencing projects and a concomitant …

[图书][B] Next generation sequencing and sequence assembly: methodologies and algorithms

A Masoudi-Nejad, Z Narimani, N Hosseinkhan - 2013 - books.google.com
The goal of this book is to introduce the biological and technical aspects of next generation
sequencing methods, as well as algorithms to assemble these sequences into whole …

Next-generation sequence assembly: four stages of data processing and computational challenges

S El-Metwally, T Hamza, M Zakaria… - PLoS computational …, 2013 - journals.plos.org
Decoding DNA symbols using next-generation sequencers was a major breakthrough in
genomic research. Despite the many advantages of next-generation sequencers, eg, the …

Tandem repeats lead to sequence assembly errors and impose multi-level challenges for genome and protein databases

OK Tørresen, B Star, P Mier… - Nucleic acids …, 2019 - academic.oup.com
The widespread occurrence of repetitive stretches of DNA in genomes of organisms across
the tree of life imposes fundamental challenges for sequencing, genome assembly, and …

Sequencing technologies—the next generation

ML Metzker - Nature reviews genetics, 2010 - nature.com
Demand has never been greater for revolutionary technologies that deliver fast, inexpensive
and accurate genome information. This challenge has catalysed the development of next …