[HTML][HTML] Experimental coronary artery stenosis accelerates kidney damage in renovascular hypertensive swine

D Sun, A Eirin, XY Zhu, X Zhang, JA Crane… - Kidney international, 2015 - Elsevier
The impact of coronary artery stenosis (CAS) on renal injury is unknown. Here we tested
whether the existence of CAS, regardless of concurrent atherosclerosis, would induce …

Hypercholesterolemia impairs nonstenotic kidney outcomes after reversal of experimental renovascular hypertension

D Sun, Z Chen, A Eirin, XY Zhu… - American journal of …, 2016 - academic.oup.com
BACKGROUND Revascularization of a stenotic renal artery improves kidney function only in
select patients with renovascular hypertension (HT) secondary to atherosclerosis. However …

Distinct renal injury in early atherosclerosis and renovascular disease

AR Chade, M Rodriguez-Porcel, JP Grande, JD Krier… - Circulation, 2002 - Am Heart Assoc
Background—Atherosclerotic renovascular disease may augment deterioration of renal
function and ischemic nephropathy compared with other causes of renal artery stenosis …

Early atherosclerosis aggravates renal microvascular loss and fibrosis in swine renal artery stenosis

D Sun, A Eirin, B Ebrahimi, SC Textor, A Lerman… - Journal of the American …, 2016 - Elsevier
Renal function in patients with atherosclerosis and renal artery stenosis (ARAS) deteriorates
more frequently than in nonatherosclerotic RAS. We hypothesized that ARAS aggravates …

Early atherosclerosis aggravates the effect of renal artery stenosis on the swine kidney

VH Urbieta-Caceres, R Lavi, XY Zhu… - American Journal …, 2010 - journals.physiology.org
Atherosclerotic renal artery stenosis (ARAS) is increasingly identified in patients with end-
stage renal disease. Renal function in ARAS patients deteriorates more frequently than in …

Reversal of experimental renovascular hypertension restores coronary microvascular function and architecture

VH Urbieta-Caceres, XY Zhu, ME Gibson… - American journal of …, 2011 - academic.oup.com
Background Hypertension (HTN) may lead to left ventricular hypertrophy and vascular
dysfunction, which are independent factors for adverse cardiovascular outcomes. We …

Persistent kidney dysfunction in swine renal artery stenosis correlates with outer cortical microvascular remodeling

A Eirin, XY Zhu, VH Urbieta-Caceres… - American Journal …, 2011 - journals.physiology.org
Percutaneous transluminal renal stenting (PTRS) does not consistently improve renal
function in patients with atherosclerotic renovascular disease, but the mechanisms …

Changes in glomerular filtration rate after renal revascularization correlate with microvascular hemodynamics and inflammation in Swine renal artery stenosis

A Eirin, B Ebrahimi, X Zhang, XY Zhu… - Circulation …, 2012 - Am Heart Assoc
Background—The selection of patients with renal artery stenosis (RAS) likely to improve
glomerular filtration rate (GFR) after percutaneous transluminal renal angioplasty is difficult …

Mechanisms of renal structural alterations in combined hypercholesterolemia and renal artery stenosis

AR Chade, M Rodriguez-Porcel… - … , and vascular biology, 2003 - Am Heart Assoc
Objective—Atherosclerotic renovascular disease (ARVD) aggravates renal scarring more
than other causes of renal artery stenosis (RAS), but the underlying pathogenic mechanisms …

Mitochondrial protection restores renal function in swine atherosclerotic renovascular disease

A Eirin, B Ebrahimi, X Zhang, XY Zhu… - Cardiovascular …, 2014 - academic.oup.com
Aims The mechanisms responsible for renal injury in atherosclerotic renovascular disease
(ARVD) are incompletely understood, and few therapeutic options are available to reverse it …