Oxytocin and the social brain: neural mechanisms and perspectives in human research

M Kanat, M Heinrichs, G Domes - Brain research, 2014 - Elsevier
The present paper summarizes functional imaging studies investigating the effects of
intranasal oxytocin (OT) on brain responses to social stimuli. We aim to integrate previous …

Oxytocin influences processing of socially relevant cues in the ventral tegmental area of the human brain

SE Groppe, A Gossen, L Rademacher, A Hahn… - Biological …, 2013 - Elsevier
Background Evidence accumulates that the neuropeptide oxytocin plays an important role in
mediating social interaction among humans and that a dysfunction in oxytocin-modulated …

Do delivery routes of intranasally administered oxytocin account for observed effects on social cognition and behavior? A two-level model

DS Quintana, GA Alvares, IB Hickie… - … & Biobehavioral Reviews, 2015 - Elsevier
Accumulating evidence demonstrates the important role of oxytocin (OT) in the modulation of
social cognition and behavior. This has led many to suggest that the intranasal …

[HTML][HTML] A spatiotemporal profile of in vivo cerebral blood flow changes following intranasal oxytocin in humans

Y Paloyelis, OM Doyle, FO Zelaya, S Maltezos… - Biological …, 2016 - Elsevier
Background Animal and human studies highlight the role of oxytocin in social cognition and
behavior and the potential of intranasal oxytocin (IN-OT) to treat social impairment in …

[HTML][HTML] Plasma oxytocin explains individual differences in neural substrates of social perception

K Lancaster, CS Carter… - Frontiers in human …, 2015 - frontiersin.org
The neuropeptide oxytocin plays a critical role in social cognition and behavior. A number of
studies using intranasal administration have demonstrated that oxytocin improves social …

In the nose or on the tongue? Contrasting motivational effects of oral and intranasal oxytocin on arousal and reward during social processing

J Kou, C Lan, Y Zhang, Q Wang, F Zhou, Z Zhao… - Translational …, 2021 - nature.com
Intranasal oxytocin exerts wide-ranging effects on socioemotional behavior and is proposed
as a potential therapeutic intervention in psychiatric disorders. However, following intranasal …

Oxytocin, brain physiology, and functional connectivity: a review of intranasal oxytocin fMRI studies

RAI Bethlehem, J Van Honk, B Auyeung… - …, 2013 - Elsevier
In recent years the neuropeptide oxytocin (OT) has become one of the most studied peptides
of the human neuroendocrine system. Research has shown widespread behavioural effects …

Statistical and methodological considerations for the interpretation of intranasal oxytocin studies

H Walum, ID Waldman, LJ Young - Biological psychiatry, 2016 - Elsevier
Over the last decade, oxytocin (OT) has received focus in numerous studies associating
intranasal administration of this peptide with various aspects of human social behavior …

Oxytocin's effect on resting-state functional connectivity varies by age and sex

NC Ebner, H Chen, E Porges, T Lin, H Fischer… - …, 2016 - Elsevier
The neuropeptide oxytocin plays a role in social cognition and affective processing. The
neural processes underlying these effects are not well understood. Modulation of …

Intranasal oxytocin effects on social cognition: a critique

SL Evans, O Dal Monte, P Noble, BB Averbeck - Brain research, 2014 - Elsevier
The last decade has seen a large number of published findings supporting the hypothesis
that intranasally delivered oxytocin (OT) can enhance the processing of social stimuli and …