In situ hybridization with cRNA probes showed A2A receptor and Golf mRNAs to be
abundantly expressed in caudate putamen, nucleus accumbens, and olfactory tubercle …

A cDNA fragment homologous to other G protein-coupled receptors was isolated from rat
brain using the PCR method and demonstrated to be abundantly expressed in striatum …

Adenosine acts as a neuromodulator through A1 and A2 receptors. The adenosine analogs
have been recognized, among other effects, as strong depressors of the locomotor activity …

We isolated and characterized a 4.8‐kb 5′ flanking region of the rat A2A adenosine
receptor (A2A‐R) gene in the present study. Promoter activity was observed with this DNA …

The A2A adenosine receptor (A2A‐AR) transcript and radioligand binding sites have a
distinct distribution in rat brain, restricted primarily to the striatum, nucleus accumbens and …

The distribution of the messenger RNA coding for the recently cloned adenosine A 2
receptor was studied in the human brain using in situ hybridization histochemistry. A 2 …

Polyclonal antisera were generated against two identical regions of rat and human A1
adenosine receptors using synthetic multiple-antigenic-peptides as immunogens. Western …

A2A adenosine receptors (A2ARs) are expressed with the greatest abundance in the
striatum and other nuclei of the basal ganglia. The segregated expression of A2ARs on the …

1. Adenosine is an endogenous neuromodulator that exerts its depressant effect on neurons
by acting on the A 1 adenosine receptor subtype. Excitatory actions of adenosine, mediated …

Recent advances in molecular biology, biochemistry, cell biology and behavioral
pharmacology together with the development of more selective ligands to the various …