Endothelial progenitor cells—an evolving story

JD Pearson - Microvascular research, 2010 - Elsevier
The first description of endothelial progenitor cells (EPC) in 1997 led rapidly to substantial
changes in our understanding of angiogenesis, and within 5 years to the first clinical studies …

Endothelial progenitor cells: implications for cardiovascular disease

S Möbius‐Winkler, R Höllriegel… - Cytometry Part A …, 2009 - Wiley Online Library
Endothelial progenitor cells (EPCs) reside in the bone marrow and are mobilized into the
circulation by specific stimuli such as certain drugs, ischemia, and exercise training. Once in …

Endothelial progenitor cells: regulation and contribution to adult neovascularization

DH Walter, S Dimmeler - Herz, 2002 - search.proquest.com
Recent studies suggest that circulating progenitor cells contribute to the formation of new
blood vessels in adults after tissue ischemia. The infusion of these progenitor cells was used …

CD34-positive cells exhibit increased potency and safety for therapeutic neovascularization after myocardial infarction compared with total mononuclear cells

A Kawamoto, H Iwasaki, K Kusano, T Murayama… - Circulation, 2006 - Am Heart Assoc
Background—We compared the therapeutic potential of purified mobilized human CD34+
cells with that of mobilized total mononuclear cells (tMNCs) for the preservation/recovery of …

Circulating endothelial progenitor cells and cardiovascular outcomes

N Werner, S Kosiol, T Schiegl, P Ahlers… - … England Journal of …, 2005 - Mass Medical Soc
Background Endothelial progenitor cells derived from bone marrow are believed to support
the integrity of the vascular endothelium. The number and function of endothelial progenitor …

CD34+ Cells Represent Highly Functional Endothelial Progenitor Cells in Murine Bone Marrow

J Yang, M Ii, N Kamei, C Alev, SM Kwon, A Kawamoto… - PloS one, 2011 - journals.plos.org
Background Endothelial progenitor cells (EPCs) were shown to have angiogenic potential
contributing to neovascularization. However, a clear definition of mouse EPCs by cell …

Circulating endothelial progenitor cells predict coronary artery disease severity

GA Kunz, G Liang, F Cuculi, D Gregg, KC Vata… - American heart …, 2006 - Elsevier
BACKGROUND: Circulating endothelial progenitor cells (EPCs) may play an important role
in the body's defense against atherosclerosis. Previous studies have shown an association …

Effects of exercise and ischemia on mobilization and functional activation of blood-derived progenitor cells in patients with ischemic syndromes: results of 3 …

M Sandri, V Adams, S Gielen, A Linke, K Lenk… - Circulation, 2005 - Am Heart Assoc
Background—Exercise training (ET) has been shown to improve regional perfusion in
ischemic syndromes. This might be partially related to a regeneration of diseased …

Assessment of the tissue distribution of transplanted human endothelial progenitor cells by radioactive labeling

A Aicher, W Brenner, M Zuhayra, C Badorff… - Circulation, 2003 - Am Heart Assoc
Background—Transplantation of endothelial progenitor cells (EPCs) improves
vascularization and left ventricular function after experimental myocardial ischemia …

Mobilization of bone marrow-derived stem cells after myocardial infarction and left ventricular function

AM Leone, S Rutella, G Bonanno, A Abbate… - European heart …, 2005 - academic.oup.com
Aims Recent data suggest that the administration of bone marrow-derived stem cells
(BMSC) might improve myocardial perfusion and left ventricular (LV) function after acute …