Bioethical issues in genome editing by CRISPR-Cas9 technology

FB Ayanoğlu, AE Elçin, YM Elçin - Turkish Journal of Biology, 2020 - journals.tubitak.gov.tr
Genome editing technologies have led to fundamental changes in genetic science. Among
them, CRISPR-Cas9 technology particularly stands out due to its advantages such as easy …

Ethical issues regarding CRISPR mediated genome editing

ZK Shinwari, F Tanveer, AT Khalil - Current issues in molecular biology, 2018 - mdpi.com
CRISPR/Cas9 has emerged as a simple, precise and most rapid genome editing
technology. With a number of promising applications ranging from agriculture and …

CRISPR/Cas9 genome editing–new and old ethical issues arising from a revolutionary technology

M Baumann - NanoEthics, 2016 - Springer
Although germline editing has been the subject of debate ever since the 1980s, it tended to
be based rather on speculative assumptions until April 2015, when CRISPR/Cas9 …

No time to waste—the ethical challenges created by CRISPR: CRISPR/Cas, being an efficient, simple, and cheap technology to edit the genome of any organism …

AL Caplan, B Parent, M Shen, C Plunkett - EMBO reports, 2015 - embopress.org
The term “CRISPR” has gained a lot of attention recently as a result of a debate among
scientists about the possibility of genetically modifying the human germ line and the ethical …

Various aspects of a gene editing system—crispr–cas9

E Janik, M Niemcewicz, M Ceremuga… - International journal of …, 2020 - mdpi.com
The discovery of clustered, regularly interspaced short palindromic repeats (CRISPR) and
their cooperation with CRISPR-associated (Cas) genes is one of the greatest advances of …

CRISPR-Cas and its wide-ranging applications: From human genome editing to environmental implications, technical limitations, hazards and bioethical issues

R Piergentili, A Del Rio, F Signore, F Umani Ronchi… - Cells, 2021 - mdpi.com
The CRISPR-Cas system is a powerful tool for in vivo editing the genome of most organisms,
including man. During the years this technique has been applied in several fields, such as …

Genome engineering through CRISPR/Cas9 technology in the human germline and pluripotent stem cells

R Vassena, B Heindryckx, R Peco… - Human reproduction …, 2016 - academic.oup.com
BACKGROUND With the recent development of CRISPR (clustered regularly interspaced
short palindromic repeats)/Cas9 genome editing technology, the possibility to genetically …

CRISPR–cas9: A history of its discovery and ethical considerations of its use in genome editing

I Gostimskaya - Biochemistry (Moscow), 2022 - Springer
The development of a method for genome editing based on CRISPR–Cas9 technology was
awarded The Nobel Prize in Chemistry in 2020, less than a decade after the discovery of all …

A glance at genome editing with CRISPR–Cas9 technology

A Barman, B Deb, S Chakraborty - Current genetics, 2020 - Springer
In recent years, CRISPR–Cas9 technology is widely acknowledged for having major
applications in the field of biotechnology for editing genome of any organism to treat a …

One small edit for humans, one giant edit for humankind? Points and questions to consider for a responsible way forward for gene editing in humans

HC Howard, CG van El, F Forzano… - European Journal of …, 2018 - nature.com
Gene editing, which allows for specific location (s) in the genome to be targeted and altered
by deleting, adding or substituting nucleotides, is currently the subject of important academic …