Hydrogel-based biocontainment of bacteria for continuous sensing and computation
Genetically modified microorganisms (GMMs) can enable a wide range of important
applications including environmental sensing and responsive engineered living materials …
applications including environmental sensing and responsive engineered living materials …
Engineered living materials based on adhesin-mediated trapping of programmable cells
S Guo, E Dubuc, Y Rave, M Verhagen… - ACS synthetic …, 2020 - ACS Publications
Engineered living materials have the potential for wide-ranging applications such as
biosensing and treatment of diseases. Programmable cells provide the functional basis for …
biosensing and treatment of diseases. Programmable cells provide the functional basis for …
Next-generation biocontainment systems for engineered organisms
The increasing use of engineered organisms for industrial, clinical, and environmental
applications poses a growing risk of spreading hazardous biological entities into the …
applications poses a growing risk of spreading hazardous biological entities into the …
Advances in preservation methods: keeping biosensor microorganisms alive and active
J Bjerketorp, S Håkansson, S Belkin… - Current opinion in …, 2006 - Elsevier
The ability of bacteria to sense their surroundings can be employed to measure the
bioavailability and toxicity of pollutants. However, long-term maintenance of both viability …
bioavailability and toxicity of pollutants. However, long-term maintenance of both viability …
Hydrogel-encapsulation to enhance bacterial diagnosis of colon inflammation
S Aghlara-Fotovat, E Musteata, MD Doerfert, M Baruch… - Biomaterials, 2023 - Elsevier
Bacteria can be genetically programmed to sense and report the presence of disease
biomarkers in the gastrointestinal (GI) tract. However, diagnostic bacteria are typically …
biomarkers in the gastrointestinal (GI) tract. However, diagnostic bacteria are typically …
Compartmentalized microbes and co-cultures in hydrogels for on-demand bioproduction and preservation
Most mono-and co-culture bioprocess applications rely on large-scale suspension
fermentation technologies that are not easily portable, reusable, or suitable for on-demand …
fermentation technologies that are not easily portable, reusable, or suitable for on-demand …
A programmable encapsulation system improves delivery of therapeutic bacteria in mice
Living bacteria therapies have been proposed as an alternative approach to treating a broad
array of cancers. In this study, we developed a genetically encoded microbial encapsulation …
array of cancers. In this study, we developed a genetically encoded microbial encapsulation …
Resilient living materials built by printing bacterial spores
LM González, N Mukhitov, CA Voigt - Nature chemical biology, 2020 - nature.com
Materials can be made multifunctional by embedding them with living cells that perform
sensing, synthesis, energy production, and physical movement. A challenge is that the …
sensing, synthesis, energy production, and physical movement. A challenge is that the …
Multilayered genetic safeguards limit growth of microorganisms to defined environments
RR Gallagher, JR Patel, AL Interiano… - Nucleic acids …, 2015 - academic.oup.com
Genetically modified organisms (GMOs) are commonly used to produce valuable
compounds in closed industrial systems. However, their emerging applications in open …
compounds in closed industrial systems. However, their emerging applications in open …
Engineered bacteria-based living materials for biotherapeutic applications
R Omer, MZ Mohsin, A Mohsin, BS Mushtaq… - … in Bioengineering and …, 2022 - frontiersin.org
Future advances in therapeutics demand the development of dynamic and intelligent living
materials. The past static monofunctional materials shall be unable to meet the requirements …
materials. The past static monofunctional materials shall be unable to meet the requirements …