Obesity-prone (OP) individuals have a significant predisposition to obesity and diabetes.
Previously, we have found that OP individuals, despite being normal in weight and BMI …

Objective: Obesity and obesity-related metabolic diseases are characterized by gut
microbiota and epigenetic alterations. Recent insight has suggested the existence of a …

The core human gut microbiota contributes to the developmental origin of diseases by
modifying metabolic pathways. To evaluate the predominant microbiota as an epigenetic …

Metabolic diseases are becoming an alarming health issue due to elevated incidences of
these diseases over the past few decades. Various environmental factors are associated …

The prevalence of metabolic diseases, including obesity, dyslipidemia, type 2 diabetes
mellitus (T2DM), and non-alcoholic fatty liver disease (NAFLD), is a severe burden in human …

Precision nutrition is an emerging area of nutrition research, with primary focus on the
individual variability in response to dietary and lifestyle factors, which are mainly determined …

Individuals with nonalcoholic fatty liver disease (NAFLD) have an altered gut microbiota
composition. Moreover, hepatic DNA methylation may be altered in the state of NAFLD …

Accumulating evidence shows that microbes with their theater of activity residing within the
human intestinal tract (ie, the gut microbiome) influence host metabolism. Some of the …

Background While the genetics of obesity has been well defined, the epigenetics of obesity
is poorly understood. Here, we used a genome-wide approach to identify genes with …

Background Obesity is a well-recognized risk factor for insulin resistance and type 2
diabetes (T2D), although the precise mechanisms underlying the relationship remain …