Shedding Light on Melanocyte Pathobiology In Vivo

MR Zaidi, EC De Fabo, FP Noonan, G Merlino - Cancer research, 2012 - AACR
Cutaneous malignant melanoma is rapidly increasing in the developed world and continues
to be a challenge in the clinic. Although extensive epidemiologic evidence points to solar UV …

The photobiology of melanocytes modulates the impact of UVA on sunlight-induced melanoma

D Mitchell, A Fernandez - Photochemical & Photobiological Sciences, 2012 - Springer
Ultraviolet radiation is responsible for melanoma. In this review, we address the role of the
different UV spectra in melanoma. The data suggest that only UVB is capable of initiating …

Cutaneous melanoma: how does ultraviolet light contribute to melanocyte transformation?

G Walker - 2008 - Taylor & Francis
Ascribing a causal role to ultraviolet radiation in melanoma induction is problematic, as the
relationship between total lifetime sun exposure and melanoma risk is not as strong as for …

[HTML][HTML] Ultraviolet radiation-mediated development of cutaneous melanoma: An update

G Emri, G Paragh, Á Tósaki, E Janka, S Kollár… - … of Photochemistry and …, 2018 - Elsevier
Ultraviolet (UV) light is absorbed by nucleic acids, proteins or other endogenous
chromophores, such as porphyrins, flavins and melanin, triggering biological processes in …

How sunlight causes melanoma

L Garibyan, DE Fisher - Current oncology reports, 2010 - Springer
The incidence of melanoma has continued to rise dramatically over the past few decades,
especially in young females. Due to the deadly nature of this disease, melanoma has …

Ultraviolet radiation and cutaneous malignant melanoma

C Jhappan, FP Noonan, G Merlino - Oncogene, 2003 - nature.com
Recent years have seen a steady rise in the incidence of cutaneous malignant melanoma
worldwide. Although it is now appreciated that the key to understanding the process by …

Mechanisms and prevention of UV‐induced melanoma

A Sample, YY He - Photodermatology, photoimmunology & …, 2018 - Wiley Online Library
Melanoma is the deadliest form of skin cancer and its incidence is rising, creating a costly
and significant clinical problem. Exposure to ultraviolet (UV) radiation, namely UVA (315 …

Recent advances in melanoma biology

C Perlis, M Herlyn - The oncologist, 2004 - academic.oup.com
Abstract Learning Objectives After completing this course, the reader will be able to: Identify
the epidemiological evidence supporting the association of intermittent sun exposure with …

Cutaneous photobiology. The melanocyte vs. the sun: who will win the final round?

AL Kadekaro, RJ Kavanagh, K Wakamatsu… - Pigment Cell …, 2003 - Wiley Online Library
Solar ultraviolet radiation (UV) is a major environmental factor that dramatically alters the
homeostasis of the skin as an organ by affecting the survival, proliferation and differentiation …

[HTML][HTML] Melanoma: Stem cells, sun exposure and hallmarks for carcinogenesis, molecular concepts and future clinical implications

A Kyrgidis, TG Tzellos, S Triaridis - Journal of carcinogenesis, 2010 - ncbi.nlm.nih.gov
Background: The classification and prognostic assessment of melanoma is currently based
on morphologic and histopathologic biomarkers. Availability of an increasing number of …