Studies on cervical cancer are urgently required to improve clinical outcomes. As a major
anticancer drug for cervical cancer, paclitaxel has been used for many years in clinical …

Cancer is a significant medical issue, being one of the main causes of mortality around the
world. The therapies for this pathology depend on the stage in which the cancer is found, but …

Cancer is a disease that claims millions of lives each year across the world. Despite
advancement in technologies and therapeutics for treating the disease, these modes are …

Since drug resistance is a complex and multifactorial event involving activation/repression of
multiple biochemical pathways, we used a proteomic approach to study cisplatin resistance …

The major obstacle in the clinical use of the antitumor drug cisplatin is inherent and acquired
resistance. Typically, cisplatin resistance is not restricted to a single mechanism demanding …

Drug resistance represents one of the greatest challenges in cancer treatment. Cancer stem
cells (CSCs), a subset of cells within the tumor with the potential for self-renewal …

Toxicity reduction of cisplatin is necessary for improved treatment of cancer. Here we have
demonstrated the synergistic growth-inhibitory effect of cisplatin on cervical cancer cells in …

Sub population of cancer cells, referred to as Cancer stem cells (CSCs) or tumor initiating
cells, have enhanced metastatic potential that drives tumor progression. CSCs have been …

The main goal of chemotherapeutic drugs is to induce massive cell death in tumors.
Cisplatin is an antitumor drug widely used to treat several types of cancer. Despite its …

Background In Cervical cancer (CC), in addition to HPV infection, the most relevant
alteration during CC initiation and progression is the aberrant activation of Wnt/β-catenin …