Highlights•Sequence and topological variation in shell proteins lead to specialization.•
Microcompartment shells proteins have varied quaternary structures.•A new online database …

Details are emerging on the structure and function of a remarkable class of capsid-like
protein assemblies that serve as simple metabolic organelles in many bacteria. These …

Some bacteria contain organelles or microcompartments consisting of a large virion-like
protein shell encapsulating sequentially acting enzymes. These organized …

Bacterial microcompartments are large supramolecular assemblies, resembling viruses in
size and shape, found inside many bacterial cells. A protein-based shell encapsulates a …

Bacterial microcompartments are organelle-like structures composed entirely of proteins.
They have evolved to carry out several distinct and specialized metabolic functions in a wide …

Highlights•MCPs are organelles uniquely suited for metabolic engineering
applications.•MCPs increase flux while protecting cells from toxic intermediates.•Insights into …

Bacterial microcompartments (BMCs) are proteinaceous organelles that are found in a
broad range of bacteria and are composed of an outer shell that encases an enzyme cargo …

Highlights•Bacterial microcompartments (BMCs) are self-assembling organelles comprising
a protein shell that encapsulates cargo enzymes.•Unraveling the composition and …

Bacterial microcompartments are bacterial analogs of eukaryotic organelles in that they
spatially segregate aspects of cellular metabolism, but they do so by building not a lipid …

As synthetic biology advances the intricacy of engineered biological systems, the
importance of spatial organization within the cellular environment must not be marginalized …