Structural characterization of a synthetic tandem-domain bacterial microcompartment shell protein capable of forming icosahedral shell assemblies

M Sutter, S McGuire, B Ferlez, CA Kerfeld - ACS synthetic biology, 2019 - ACS Publications
Bacterial microcompartments are subcellular compartments found in many prokaryotes; they
consist of a protein shell that encapsulates enzymes that perform a variety of functions. The …

Assembly of robust bacterial microcompartment shells using building blocks from an organelle of unknown function

JK Lassila, SL Bernstein, JN Kinney, SD Axen… - Journal of Molecular …, 2014 - Elsevier
Bacterial microcompartments (BMCs) sequester enzymes from the cytoplasmic environment
by encapsulation inside a selectively permeable protein shell. Bioinformatic analyses …

[PDF][PDF] The plasticity of molecular interactions governs bacterial microcompartment shell assembly

BJ Greber, M Sutter, CA Kerfeld - Structure, 2019 - cell.com
Bacterial microcompartments (BMCs) are composed of an enzymatic core encapsulated by
a selectively permeable protein shell that enhances catalytic efficiency. Many pathogenic …

Bacterial microcompartments: widespread prokaryotic organelles for isolation and optimization of metabolic pathways

TA Bobik, BP Lehman, TO Yeates - Molecular microbiology, 2015 - Wiley Online Library
Prokaryotes use subcellular compartments for a variety of purposes. An intriguing example
is a family of complex subcellular organelles known as bacterial microcompartments (MCP …

Diverse bacterial microcompartment organelles

C Chowdhury, S Sinha, S Chun… - Microbiology and …, 2014 - Am Soc Microbiol
Bacterial microcompartments (MCPs) are sophisticated protein-based organelles used to
optimize metabolic pathways. They consist of metabolic enzymes encapsulated within a …

Biophysical approaches to understand and re-purpose bacterial microcompartments

G Kumar, S Sinha - Current Opinion in Microbiology, 2021 - Elsevier
Highlightsand crystallography allows a comprehensive understanding of the morphology
and structure of BMCs.•TEM, Cryo-TEM and AFM allow visualization of shell protein …

The shells of BMC-type microcompartment organelles in bacteria

TO Yeates, J Jorda, TA Bobik - Journal of molecular microbiology and …, 2013 - karger.com
Bacterial microcompartments are large proteinaceous structures that act as metabolic
organelles in many bacterial cells. A shell or capsid, which is composed of a few thousand …

Bacterial microcompartment shells of diverse functional types possess pentameric vertex proteins

NM Wheatley, SD Gidaniyan, Y Liu, D Cascio… - Protein …, 2013 - Wiley Online Library
Bacterial microcompartments (MCPs) are large proteinaceous structures comprised of a
roughly icosahedral shell and a series of encapsulated enzymes. MCPs carrying out three …

Bacterial microcompartments

CA Kerfeld, C Aussignargues, J Zarzycki… - Nature Reviews …, 2018 - nature.com
Bacterial microcompartments (BMCs) are self-assembling organelles that consist of an
enzymatic core that is encapsulated by a selectively permeable protein shell. The potential …

Symmetry breaking and structural polymorphism in a bacterial microcompartment shell protein for choline utilization

JM Ochoa, VN Nguyen, M Nie, MR Sawaya… - Protein …, 2020 - Wiley Online Library
Bacterial microcompartments are protein‐based organelles that carry out specialized
metabolic functions in diverse bacteria. Their outer shells are built from several thousand …