Selenium status is associated with colorectal cancer risk in the European prospective investigation of cancer and nutrition cohort

DJ Hughes, V Fedirko, M Jenab… - … journal of cancer, 2015 - Wiley Online Library
Suboptimal intakes of the micronutrient selenium (Se) are found in many parts of Europe.
Low Se status may contribute to colorectal cancer (CRC) development. We assessed Se …

[HTML][HTML] Prediagnostic selenium status and hepatobiliary cancer risk in the European Prospective Investigation into Cancer and Nutrition cohort

DJ Hughes, T Duarte-Salles, S Hybsier… - The American journal of …, 2016 - Elsevier
Background: Selenium status is suboptimal in many Europeans and may be a risk factor for
the development of various cancers, including those of the liver and biliary tract. Objective …

Selenium supplementation and colorectal adenomas: an analysis of the nutritional prevention of cancer trial

ME Reid, AJ Duffield‐Lillico, A Sunga… - … journal of cancer, 2006 - Wiley Online Library
Selenium status has been inversely associated with colorectal cancers (CRC) and
adenomas. This investigation evaluates the association between selenium supplementation …

The influence of selenium and selenoprotein gene variants on colorectal cancer risk

C Méplan, J Hesketh - Mutagenesis, 2012 - academic.oup.com
Colorectal cancer (CRC) is a major cause of mortality throughout the world and risk of CRC
is known to be modulated by nutritional factors. Low intake of the micronutrient selenium …

High serum selenium and reduced risk of advanced colorectal adenoma in a colorectal cancer early detection program

U Peters, N Chatterjee, TR Church, C Mayo… - … Biomarkers & Prevention, 2006 - AACR
Background: Epidemiologic and animal studies suggest that selenium may reduce risk of
colorectal cancer. However, the epidemiologic data is mainly from relatively small …

Expression of selenoprotein genes and association with selenium status in colorectal adenoma and colorectal cancer

DJ Hughes, T Kunická, L Schomburg, V Liška, N Swan… - Nutrients, 2018 - mdpi.com
Dietary selenium (Se) intake is essential for synthesizing selenoproteins that are important
in countering oxidative and inflammatory processes linked to colorectal carcinogenesis …

Selenium and colorectal adenoma: results of a pooled analysis

ET Jacobs, R Jiang, DS Alberts… - Journal of the …, 2004 - academic.oup.com
Background: Secondary analyses of data from a large randomized clinical trial have
suggested that intake of the trace element selenium reduces risk of colorectal neoplasia, but …

Plasma selenium levels and the risk of colorectal adenomas

MW Russo, SC Murray, JI Wurzelmann, JT Woosley… - 1997 - Taylor & Francis
Previous research has suggested that selenium may protect against the development of
colorectal neoplasia. We examined the potential chemopreventive properties of selenium …

[HTML][HTML] Ecologic study of serum selenium and upper gastrointestinal cancers in Iran

M Nouraie, A Pourshams, F Kamangar… - World journal of …, 2004 - ncbi.nlm.nih.gov
AIM: Both observational and experimental studies have shown that higher selenium status
reduces the risk of upper gastrointestinal cancers in selenium deficient populations. Recent …

Baseline characteristics and the effect of selenium supplementation on cancer incidence in a randomized clinical trial: a summary report of the Nutritional Prevention …

AJ Duffield-Lillico, ME Reid, BW Turnbull… - … Biomarkers & Prevention, 2002 - AACR
Abstract The Nutritional Prevention of Cancer Trial was a randomized, clinical trial designed
to evaluate the efficacy of selenium asselenized yeast (200 μg daily) in preventing …