The integron: adaptation on demand
The integron is a powerful system which, by capturing, stockpiling, and rearranging new
functions carried by gene encoding cassettes, confers upon bacteria a rapid adaptation …
functions carried by gene encoding cassettes, confers upon bacteria a rapid adaptation …
Evolution of class 1 integrons: mobilization and dispersal via food-borne bacteria
Class 1 integrons have played a major role in the global dissemination of antibiotic
resistance. Reconstructing the history of class 1 integrons might help us control further …
resistance. Reconstructing the history of class 1 integrons might help us control further …
[HTML][HTML] Resistance integrons and super-integrons
AC Fluit, FJ Schmitz - Clinical microbiology and infection, 2004 - Elsevier
Integrons are genetic elements composed of a gene encoding an integrase, gene cassettes
and an integration site for the gene cassettes (att). The integrase excises and integrates the …
and an integration site for the gene cassettes (att). The integrase excises and integrates the …
The peril and promise of integrons: beyond antibiotic resistance
Integrons are bacterial genetic elements that can capture, rearrange, and express mobile
gene cassettes. They are best known for their role in disseminating antibiotic-resistance …
gene cassettes. They are best known for their role in disseminating antibiotic-resistance …
Prevalence and characterization of integrons in blood culture Enterobacteriaceae and gastrointestinal Escherichia coli in Norway and reporting of a novel class 1 …
E Heir, BA Lindstedt, TM Leegaard, E Gjernes… - Annals of clinical …, 2004 - Springer
Background Class 1 integrons contain genetic elements for site-specific recombination,
capture and mobilization of resistance genes. Studies investigating the prevalence …
capture and mobilization of resistance genes. Studies investigating the prevalence …
Gene cassettes encoding resistance to quaternary ammonium compounds: a role in the origin of clinical class 1 integrons?
MR Gillings, D Xuejun, SA Hardwick… - The ISME …, 2009 - academic.oup.com
DNA sequencing, phylogenetic and mapping studies suggest that the class 1 integron found
in pathogens arose when one member of the diverse family of environmental class 1 …
in pathogens arose when one member of the diverse family of environmental class 1 …
PCR mapping of integrons reveals several novel combinations of resistance genes
C Levesque, L Piche, C Larose… - Antimicrobial agents and …, 1995 - Am Soc Microbiol
The integron is a new type of mobile element which has evolved by a site-specific
recombinational mechanism. Integrons consist of two conserved segments of DNA …
recombinational mechanism. Integrons consist of two conserved segments of DNA …
The role of integrons in antibiotic resistance gene capture
DA Rowe-Magnus, D Mazel - International Journal of Medical Microbiology, 2002 - Elsevier
Although recently discovered, integrons have played a primordial role in the evolution of
bacterial genomes. They are best known as the genetic agents responsible for the capture …
bacterial genomes. They are best known as the genetic agents responsible for the capture …
Quantitative multiplex real-time PCR for detecting class 1, 2 and 3 integrons
O Barraud, MC Baclet, F Denis… - Journal of antimicrobial …, 2010 - academic.oup.com
Objectives Integrons are bacterial genetic elements that can capture and express genes
contained in mobile cassettes. Integrons have been described worldwide in Gram-negative …
contained in mobile cassettes. Integrons have been described worldwide in Gram-negative …
Recovery of new integron classes from environmental DNA
BS Nield, AJ Holmes, MR Gillings… - FEMS Microbiology …, 2001 - academic.oup.com
Integrons are genetic elements known for their role in the acquisition and expression of
genes conferring antibiotic resistance. Such acquisition is mediated by an integron-encoded …
genes conferring antibiotic resistance. Such acquisition is mediated by an integron-encoded …