Riboflavin is an important water soluble vitamin (B2) required for metabolic reactions,
normal cellular growth, differentiation and function. Mammalian brain cells cannot …

Drug delivery to the retina is a challenging task owing to its complex physiology and
presence of the blood-retinal barrier (BRB), which regulates the permeation of substances …

Absorption of riboflavin is mediated by transporter (s). However, a mammalian riboflavin
transporter has yet to be identified. In the present study, the novel human and rat riboflavin …

This study addresses the transport mechanism of riboflavin (vitamin B2) across intestinal
epithelium in the presence and absence of pharmacologically active compounds. A …

The previous in vivo study revealed the carrier-mediated transport of riboflavin (vitamin B 2)
across the blood-retinal barrier (BRB). In the present study, the blood-to-retina supply of …

We isolated cDNA coding a new human riboflavin transporter (hRFT) 3, which exhibits 86.7
and 44.1% amino acid identity with hRFT1 and hRFT2, respectively. It was predicted to have …

The role of riboflavin in cell maintenance and growth, and the mechanism by which it is
absorbed into various human tissues and cell lines has been extensively studied over the …

The retention and cellular internalization of drug delivery systems and theranostics for
cancer therapy can be improved by targeting molecules. Since an increased uptake of …

We have newly identified rat riboflavin transporter 2 (rRFT2) and its human orthologue
(hRFT2), and carried out detailed functional characterization of rRFT2. The mRNA of rRFT2 …

Riboflavin, also known as vitamin B2, is transported across the biological membrane into
various organs by transport systems. Riboflavin transporter RFVT3 is expressed in the small …