Abstract p300/CBP is a transcriptional adaptor that integrates signals from many sequence-
specific activators via direct interactions. Various cellular and viral factors target p300/CBP to …

Nucleosomal histone modification is believed to be a critical step in the activation of RNA
polymerase II–dependent transcription. p300/CBP and PCAF histone acetyltransferases …

A number of transcriptional coactivators possess intrinsic histone acetylase activity,
providing a direct link between hyperacetylated chromatin and transcriptional activation. We …

p300/CBP transcriptional co-activator proteins play a central role in co-ordinating and
integrating multiple signal-dependent events with the transcription apparatus, allowing the …

Background The coactivator p300 acts as a transcriptional adaptor for many DNA‐binding
activators. The finding that p300 possesses intrinsic acetyltransferase activity which, by …

The transcriptional coactivator p300 shows physical and functional interactions with a
diverse group of activators and contains an intrinsic acetyltransferase activity whose exact …

The p300/cAMP response element-binding protein-binding protein (CBP) family members
include human p300 and cAMP response element-binding protein-binding protein, which …

CREB-binding proteins (CBP) and p300 are essential transcriptional coactivators for a large
number of regulated DNA-binding transcription factors, including CREB, nuclear receptors …

Abstract p300 and CBP participate as transcriptional coregulators in the execution of a wide
spectrum of cellular gene expression programs controlling cell differentiation, growth and …

Transforming viral proteins such as E1A which force quiescent cells into S phase have two
essential cellular target proteins, Rb and CBP/p300. Rb regulates the G1/S transition by …