[HTML][HTML] The transcriptional coactivators p300 and CBP are histone acetyltransferases
VV Ogryzko, RL Schiltz, V Russanova, BH Howard… - Cell, 1996 - cell.com
Abstract p300/CBP is a transcriptional adaptor that integrates signals from many sequence-
specific activators via direct interactions. Various cellular and viral factors target p300/CBP to …
specific activators via direct interactions. Various cellular and viral factors target p300/CBP to …
[HTML][HTML] A viral mechanism for inhibition of p300 and PCAF acetyltransferase activity
Nucleosomal histone modification is believed to be a critical step in the activation of RNA
polymerase II–dependent transcription. p300/CBP and PCAF histone acetyltransferases …
polymerase II–dependent transcription. p300/CBP and PCAF histone acetyltransferases …
[HTML][HTML] Overlapping but distinct patterns of histone acetylation by the human coactivators p300 and PCAF within nucleosomal substrates
RL Schiltz, CA Mizzen, A Vassilev, RG Cook… - Journal of Biological …, 1999 - ASBMB
A number of transcriptional coactivators possess intrinsic histone acetylase activity,
providing a direct link between hyperacetylated chromatin and transcriptional activation. We …
providing a direct link between hyperacetylated chromatin and transcriptional activation. We …
p300/CBP proteins: HATs for transcriptional bridges and scaffolds
HM Chan, NB La Thangue - Journal of cell science, 2001 - journals.biologists.com
p300/CBP transcriptional co-activator proteins play a central role in co-ordinating and
integrating multiple signal-dependent events with the transcription apparatus, allowing the …
integrating multiple signal-dependent events with the transcription apparatus, allowing the …
Regulation of interaction of the acetyltransferase region of p300 and the DNA‐binding domain of Sp1 on and through DNA binding
Background The coactivator p300 acts as a transcriptional adaptor for many DNA‐binding
activators. The finding that p300 possesses intrinsic acetyltransferase activity which, by …
activators. The finding that p300 possesses intrinsic acetyltransferase activity which, by …
[HTML][HTML] Activator-dependent transcription from chromatin in vitro involving targeted histone acetylation by p300
The transcriptional coactivator p300 shows physical and functional interactions with a
diverse group of activators and contains an intrinsic acetyltransferase activity whose exact …
diverse group of activators and contains an intrinsic acetyltransferase activity whose exact …
[HTML][HTML] Transcriptional coactivator protein p300
PR Thompson, H Kurooka, Y Nakatani… - Journal of Biological …, 2001 - ASBMB
The p300/cAMP response element-binding protein-binding protein (CBP) family members
include human p300 and cAMP response element-binding protein-binding protein, which …
include human p300 and cAMP response element-binding protein-binding protein, which …
Factor-specific modulation of CREB-binding protein acetyltransferase activity
CREB-binding proteins (CBP) and p300 are essential transcriptional coactivators for a large
number of regulated DNA-binding transcription factors, including CREB, nuclear receptors …
number of regulated DNA-binding transcription factors, including CREB, nuclear receptors …
Plant orthologs of p300/CBP: conservation of a core domain in metazoan p300/CBP acetyltransferase-related proteins
L Bordoli, M Netsch, U Lüthi, W Lutz… - Nucleic Acids …, 2001 - academic.oup.com
Abstract p300 and CBP participate as transcriptional coregulators in the execution of a wide
spectrum of cellular gene expression programs controlling cell differentiation, growth and …
spectrum of cellular gene expression programs controlling cell differentiation, growth and …
CBP/p300 histone acetyl-transferase activity is important for the G1/S transition
S Ait-Si-Ali, A Polesskaya, S Filleur, R Ferreira… - Oncogene, 2000 - nature.com
Transforming viral proteins such as E1A which force quiescent cells into S phase have two
essential cellular target proteins, Rb and CBP/p300. Rb regulates the G1/S transition by …
essential cellular target proteins, Rb and CBP/p300. Rb regulates the G1/S transition by …