Advances in biochemical and functional roles of angiotensin-converting enzyme 2 and angiotensin-(1–7) in regulation of cardiovascular function
CM Ferrario, AJ Trask… - American Journal of …, 2005 - journals.physiology.org
Angiotensin-converting enzyme 2 (ACE2) is the first human homologue of ACE to be
described. ACE2 is a type I integral membrane protein that functions as a carboxypeptidase …
described. ACE2 is a type I integral membrane protein that functions as a carboxypeptidase …
Angiotensin-converting enzyme 2 and new insights into the renin–angiotensin system
DW Lambert, NM Hooper, AJ Turner - Biochemical pharmacology, 2008 - Elsevier
Components of the renin–angiotensin system are well established targets for
pharmacological intervention in a variety of disorders. Many such therapies abrogate the …
pharmacological intervention in a variety of disorders. Many such therapies abrogate the …
[HTML][HTML] ACE2, a new regulator of the renin–angiotensin system
LM Burrell, CI Johnston, C Tikellis… - Trends in Endocrinology & …, 2004 - cell.com
Angiotensin-converting enzyme (ACE) is a zinc metalloproteinase and a key regulator of the
renin–angiotensin system (RAS). ACE2 is a newly described enzyme identified in rodents …
renin–angiotensin system (RAS). ACE2 is a newly described enzyme identified in rodents …
Angiotensin-converting enzyme II in the heart and the kidney
U Danilczyk, JM Penninger - Circulation research, 2006 - Am Heart Assoc
The renin-angiotensin system (RAS) has been recognized for many years as critical
pathway for blood pressure control and kidney functions. Although most of the well-known …
pathway for blood pressure control and kidney functions. Although most of the well-known …
[HTML][HTML] Angiotensin-converting enzyme 2 and angiotensin 1–7: novel therapeutic targets
F Jiang, J Yang, Y Zhang, M Dong, S Wang… - Nature Reviews …, 2014 - nature.com
The renin–angiotensin system (RAS) has pivotal roles in the regulation of normal physiology
and the pathogenesis of cardiovascular disease. Angiotensin-converting enzyme (ACE) 2 …
and the pathogenesis of cardiovascular disease. Angiotensin-converting enzyme (ACE) 2 …
[HTML][HTML] ACE and ACE2: their role to balance the expression of angiotensin II and angiotensin-(1–7)
MC Chappel, CM Ferrario - Kidney international, 2006 - Elsevier
The discovery of angiotensin-converting enzyme 2 (ACE-2) has revealed a far more
complex enzymatic cascade that may influence the renin-angiotensin system within the …
complex enzymatic cascade that may influence the renin-angiotensin system within the …
Angiotensin‐converting enzyme 2: the first decade
NE Clarke, AJ Turner - International journal of hypertension, 2012 - Wiley Online Library
The renin‐angiotensin system (RAS) is a critical regulator of hypertension, primarily through
the actions of the vasoactive peptide Ang II, which is generated by the action of angiotensin …
the actions of the vasoactive peptide Ang II, which is generated by the action of angiotensin …
Angiotensin-converting enzyme 2: implications for blood pressure and kidney disease
JR Ingelfinger - Current opinion in nephrology and hypertension, 2009 - journals.lww.com
Angiotensin-converting enzyme 2: implications for blood pres... : Current Opinion in Nephrology
and Hypertension Angiotensin-converting enzyme 2: implications for blood pressure and kidney …
and Hypertension Angiotensin-converting enzyme 2: implications for blood pressure and kidney …
ACE2: a new target for cardiovascular disease therapeutics
MK Raizada, AJ Ferreira - Journal of cardiovascular …, 2007 - journals.lww.com
The discovery of angiotensin-converting enzyme 2 (ACE2) in 2000 is an important event in
the renin-angiotensin system (RAS) story. This enzyme, an homolog of ACE, hydrolyzes …
the renin-angiotensin system (RAS) story. This enzyme, an homolog of ACE, hydrolyzes …
The role of ACE2 in cardiovascular physiology
The renin–angiotensin system (RAS) is critically involved in cardiovascular and renal
function and in disease conditions, and has been shown to be a far more complex system …
function and in disease conditions, and has been shown to be a far more complex system …