Anti-inflammatory in vitro activities of eleven selected caffeic acid derivatives based on a combination of pro−/anti-inflammatory cytokine secretions and principal …

TY Wu, CC Chen, JY Lin - Food Chemistry, 2024 - Elsevier
Eleven compounds including caffeic acid (CA), 4 kinds of caffeoylquinic acid (CQA) and 6
kinds of dicaffeoylquinic acid (DCQA), were selected to evaluate the anti-inflammatory …

Anti-inflammatory effect of caffeic acid methyl ester and its mode of action through the inhibition of prostaglandin E2, nitric oxide and tumor necrosis factor-α production

KM Shin, IT Kim, YM Park, J Ha, JW Choi… - Biochemical …, 2004 - Elsevier
The anti-inflammatory effects of caffeic acid (CA), caffeic acid methyl ester (CM) and di-O-
acetylcaffeic acid (DAC) were investigated in rats using the carrageenin-induced edema …

IRAK1/4‐targeted anti‐inflammatory action of caffeic acid

WS Yang, D Jeong, YS Yi, JG Park… - Mediators of …, 2013 - Wiley Online Library
Caffeic acid (CA) is a phenolic compound that is frequently present in fruits, grains, and
dietary supplements. Although CA has been reported to display various biological activities …

Anti-inflammatory effect of 4, 5-dicaffeoylquinic acid on RAW264. 7 cells and a rat model of inflammation

G Jang, S Lee, J Hong, B Park, D Kim, C Kim - Nutrients, 2021 - mdpi.com
Anti-inflammatory agents that are safer and more effective than the currently used non-
steroidal anti-inflammatory drugs are urgently needed. The dicaffeoylquinic acid (diCQA) …

Caffeic acid derivatives: in vitro and in vivo anti-inflammatory properties

FM Da Cunha, D Duma, J Assreuy, FC Buzzi… - Free radical …, 2004 - Taylor & Francis
<!? tlsb=. 005w> Caffeic acid and some of its derivatives such as caffeic acid phenetyl ester
(CAPE) and octyl caffeate are potent antioxidants which present important anti-inflammatory …

Amaranth's 2-caffeoylisocitric acid—An anti-inflammatory caffeic acid derivative that impairs NF-κB signaling in LPS-challenged RAW 264.7 macrophages

D Schröter, S Neugart, M Schreiner, T Grune, S Rohn… - Nutrients, 2019 - mdpi.com
For centuries, Amaranthus sp. were used as food, ornamentals, and medication. Molecular
mechanisms, explaining the health beneficial properties of amaranth, are not yet …

Chlorogenic acid (CGA) isomers alleviate interleukin 8 (IL-8) production in Caco-2 cells by decreasing phosphorylation of p38 and increasing cell integrity

N Liang, DD Kitts - International Journal of Molecular Sciences, 2018 - mdpi.com
The objective of this study was to determine the effect of six chlorogenic acid (CGA) isomers
known to be present in coffee and other plant foods on modulating the inflammatory …

Anti-inflammatory effects of Chrysophyllum cainito fruit extract in lipopolysaccharide-stimulated mouse peritoneal macrophages

VE Arana-Argáez, GJ Mena-Rejón… - …, 2021 - Springer
The present paper sought to investigate the in vitro and in vivo anti-inflammatory effects of
the methanolic extract (ME), hexane–ethyl acetate fraction E (FE) found in Chrysophyllum …

Effects of caffeine and 5-caffeoylquinic acid on blood cell in vitro cytokine production in response to lipopolysaccharide stimulation

L Rodas, S Martínez, A Riera-Sampol, HJ Moir… - Applied Sciences, 2022 - mdpi.com
Previous in vitro studies the have suggested anti-inflammatory properties of caffeine. Coffee
is also rich in phenolic acids with several potential health benefits (chlorogenic acids) …

Dicaffeoylquinic acids in Yerba mate (Ilex paraguariensis St. Hilaire) inhibit NF‐κB nucleus translocation in macrophages and induce apoptosis by activating …

S Puangpraphant, MA Berhow… - Molecular nutrition & …, 2011 - Wiley Online Library
Scope: The biological functions of caffeoylquinic acid (CQA) derivatives from various plant
sources have been partially elucidated. The objectives were to isolate and purify diCQAs …