U-box proteins, as well as other proteins involved in regulated protein degradation, are
apparently over-represented in Arabidopsis compared with other model eukaryotes. The …

Ubiquitin-mediated proteolysis is an integral part of diverse cellular functions, and of the
three enzymes involved in linking ubiquitin to protein targets, the E3 ubiquitin ligases are of …

The variance of the U-box domain in 64 Arabidopsis thaliana (thale cress) E3s (ubiquitin-
protein ligases) was used to examine the interactions between E3s and E2s (ubiquitin …

The U-box is a highly conserved domain recently identified at the C terminus of yeast UFD2,
an E4 ubiquitination factor. In yeast, UFD2 is the only U-box-containing protein, but there are …

The ubiquitin-26S proteasome system is important in the quality control of intracellular
proteins. The ubiquitin-26S proteasome system includes the E1 (ubiquitin activating), E2 …

Posttranslational modifications add complexity and diversity to cellular proteomes. One of
the most prevalent modifications across eukaryotes is ubiquitination, which is orchestrated …

Ubiquitin ligases play a central role in determining the specificity of the ubiquitination system
by selecting a myriad of appropriate candidate proteins for modification. The U-box is a …

Ubiquitin‐specific proteases (UBPs) are a highly conserved family of proteins in eukaryotes,
and play critical roles in protein de‐ubiquitination. Here we report a systematic genetic and …

Abstract p97/CDC48 is a major AAA-ATPase that acts in many cellular events such as
ubiquitin-dependent degradation and membrane fusion. Its specificity depends on a set of …

The plant U‐box (PUB) protein functions as an E3 ligase to poly‐ubiquitinate a target protein
for its degradation or post‐translational modification. Here, we report functional roles for …