All cells employ architectural proteins to confine and organize their chromosomes, and to
prevent the otherwise thermodynamically favored collapse of concentrated DNA into …

Bacterial nucleoid is a dynamic entity that changes its three-dimensional shape and
compaction depending on cellular physiology. While these changes are tightly associated …

The apparatus required for the regulation of gene expression varies widely in complexity. At
one extreme, regulation can be achieved by one or two proteins acting at a DNA locus that …

The abundant bacterial protein called HU has the ability to wrap and bend DNAin vitro, and
thus it has long been thought to play a role in DNA supercoiling. In the absence of HU …

Nucleoid-associated proteins belong to a group of small but abundant proteins in bacterial
cells. These transcription regulators are responsible for many important cellular processes …

The histone-like protein HU from Escherichia coli is involved in DNA compaction and in
processes such as DNA repair and recombination. Its participation in these events is …

As in eukaryotes, bacterial genomes are not randomly folded. Bacterial genetic information
is generally carried on a circular chromosome with a single origin of replication from which …

In mesophilic prokaryotes, the DNA-binding protein HU participates in nucleoid organization
as well as in regulation of DNA-dependent processes. Little is known about nucleoid …

The bacterial genome is folded into a compact structure called the nucleoid. Considerable
compaction of the DNA molecule is required in order to reduce its volume below that of the …

Histone-like proteins in bacteria contribute to the control of gene expression, as well as
participating in other DNA transactions such as recombination and DNA replication. They …