Rat cDNA encoding a 372-amino-acid peroxin was isolated, primarily by functional
complementation screening, using a peroxisome-deficient Chinese hamster ovary cell …

The peroxin Pex19p functions in peroxisomal membrane assembly. Here we mapped
functional domains of human Pex19p comprising 299 amino acids. Pex19p mutants deleted …

Rat cDNA encoding a 376-amino acid peroxin was isolated by functional complementation
of a peroxisome-deficient Chinese hamster ovary cell mutant, ZP110, of complementation …

Pex3p and Pex19p are key players in the post-translational import of peroxisomal
membrane proteins. New data suggest that these peroxins act in tandem, Pex19p as a …

Proteins essential for the assembly of functional peroxisomes are designated peroxins and
are encoded by PEX genes. In yeast, Pex3p was previously identified as a peroxisomal …

The peroxins Pex19 and Pex3 play an indispensable role in peroxisomal membrane protein
(PMP) biogenesis, peroxisome division, and inheritance. Pex19 plays multiple roles in these …

The molecular machinery underlying peroxisomal membrane biogenesis is not well
understood. The observation that cells deficient in the peroxins Pex3p, Pex16p, and Pex19p …

During peroxisomal matrix protein import, the peroxisomal targeting signal receptors
recognize cargo in the cytosol and interact with docking and translocation subcomplexes on …

The assembly of proteins in the peroxisomal membrane is a multistep process requiring their
recognition in the cytosol, targeting to and insertion into the peroxisomal membrane, and …

The organization of eukaryotic cells into membrane‐bound compartments must be faithfully
sustained for survival of the cell. A subtle equilibrium exists between the degradation and …