Chemerin-9, a potent agonist of chemerin receptor (ChemR23), prevents atherogenesis

K Sato, H Yoshizawa, T Seki, R Shirai… - Clinical …, 2019 - portlandpress.com
Plasma levels of chemerin, an adipocytokine produced from the adipose tissues and liver,
are associated with metabolic syndrome and coronary artery disease (CAD). Chemerin and …

Identification of chemerin receptor (ChemR23) in human endothelial cells: chemerin-induced endothelial angiogenesis

J Kaur, R Adya, BK Tan, J Chen… - … and biophysical research …, 2010 - Elsevier
Chemerin acting via its distinct G protein-coupled receptor CMKLR1 (ChemR23), is a novel
adipokine, circulating levels of which are raised in inflammatory states. Chemerin shows …

Chemerin is associated with markers of inflammation and components of the metabolic syndrome but does not predict coronary atherosclerosis

M Lehrke, A Becker, M Greif, R Stark… - European journal of …, 2009 - academic.oup.com
Objectives Chemerin is a recently discovered adipokine that regulates adipocyte
differentiation and modulates chemotaxis and activation of dendritic cells and macrophages …

Chemerin connects fat to arterial contraction

SW Watts, AM Dorrance, ME Penfold… - … , and vascular biology, 2013 - Am Heart Assoc
Objective—Obesity and hypertension are comorbid in epidemic proportion, yet their
biological connection is largely a mystery. The peptide chemerin is a candidate for …

Chemerin regulates crosstalk between adipocytes and vascular cells through Nox

KB Neves, A Nguyen Dinh Cat, RAM Lopes, FJ Rios… - …, 2015 - Am Heart Assoc
Adipocytes produce adipokines, including chemerin, a chemoattractant that mediates effects
through its ChemR23 receptor. Chemerin has been linked to endothelial dysfunction and …

[HTML][HTML] Chemerin and CMKLR1 expression in human arteries and periadventitial fat: a possible role for local chemerin in atherosclerosis?

CG Kostopoulos, SG Spiroglou, JN Varakis… - BMC Cardiovascular …, 2014 - Springer
Background Depending on their anatomical location, different fat depots have a different
capacity to produce bioactive peptides, called adipokines. Adipokines produced by …

[HTML][HTML] Relationship between chemerin levels and cardiometabolic parameters and degree of coronary stenosis in Korean patients with coronary artery disease

YJ Hah, NK Kim, MK Kim, HS Kim… - Diabetes & …, 2011 - synapse.koreamed.org
Background Chemerin is a novel adipokine that is associated with inflammation and
adipogenesis. However, it remains unclear whether chemerin is involved in patients with …

Chemerin as an independent predictor of cardiovascular event risk

S İnci, G Aksan, P Doğan - Therapeutic advances in …, 2016 - journals.sagepub.com
Currently, coronary artery disease (CAD) is considered a major ailment in humans with
widespread prevalence. CAD also accounts for high mortality rates around the world that …

Chemerin inhibits vascular calcification through ChemR23 and is associated with lower coronary calcium in chronic kidney disease

M Carracedo, A Witasp, AR Qureshi… - Journal of Internal …, 2019 - Wiley Online Library
Background Chemerin is an adipokine that signals through the G protein‐coupled receptor
ChemR23 and is associated with inflammation, glucose homeostasis, lipid metabolism and …

Low dose aspirin is associated with plasma chemerin levels and may reduce adipose tissue inflammation

M Herová, M Schmid, C Gemperle, C Loretz… - Atherosclerosis, 2014 - Elsevier
Chemerin is a peptide chemoattractant for macrophages and an adipokine regulating
adipocyte differentiation and metabolism. Plasma chemerin is increased in chronic …