[HTML][HTML] Kaempferol suppresses lipid accumulation in macrophages through the downregulation of cluster of differentiation 36 and the upregulation of scavenger …

XY Li, LX Kong, J Li, HX He… - … journal of molecular …, 2013 - spandidos-publications.com
The accumulation of foam cells in atherosclerotic lesions is a hallmark of early-stage
atherosclerosis. Kaempferol has been shown to inhibit oxidized low-density lipoprotein …

[HTML][HTML] Hesperetin inhibits foam cell formation and promotes cholesterol efflux in THP-1-derived macrophages by activating LXRα signal in an AMPK-dependent …

X Chen, D Zou, X Chen, H Wu, D Xu - Journal of physiology and …, 2021 - Springer
Cholesterol efflux from macrophages is the first step of reverse cholesterol transport (RCT),
whose increase inhibits cholesterol accumulation and foam cell formation to suppress …

EGb761 ameliorates the formation of foam cells by regulating the expression of SR-A and ABCA1: role of haem oxygenase-1

JY Tsai, KH Su, SK Shyue, YR Kou, YB Yu… - Cardiovascular …, 2010 - academic.oup.com
Aims Accumulation of foam cells in the intima is a hallmark of early-stage atherosclerotic
lesions. Ginkgo biloba extract (EGb761) has been reported to exert anti-oxidative and anti …

Anthocyanin extracted from Hibiscus attenuate oxidized LDL-mediated foam cell formation involving regulation of CD36 gene

ES Kao, TH Tseng, HJ Lee, KC Chan… - Chemico-Biological …, 2009 - Elsevier
A recent investigation highlighted that oxidative modification of low-density lipoprotein
(oxLDL) is involved in the pathogenesis of atherosclerotic lesions through the formation of …

[HTML][HTML] Inhibitory effects of resveratrol on foam cell formation are mediated through monocyte chemotactic protein-1 and lipid metabolism-related proteins

W Dong, X Wang, S Bi, Z Pan… - International …, 2014 - spandidos-publications.com
Resveratrol has been shown to exert anti-atherosclerotic effects. 5'AMP-activated protein
kinase (AMPK) and monocyte chemotactic protein-1 (MCP-1) play key roles in foam cell …

Curcumin inhibits oxLDL-induced CD36 expression and foam cell formation through the inhibition of p38 MAPK phosphorylation

K Min, HJ Um, KH Cho, TK Kwon - Food and Chemical Toxicology, 2013 - Elsevier
The uptake of oxidized low density lipoprotein (oxLDL) via scavenger receptors transforms
macrophages into foam cells, which are a hallmark of atherosclerosis. OxLDL markedly …

[HTML][HTML] Hydroxytyrosol Reduces Foam Cell Formation and Endothelial Inflammation Regulating the PPARγ/LXRα/ABCA1 Pathway

S Franceschelli, F De Cecco, M Pesce, P Ripari… - International journal of …, 2023 - mdpi.com
Cholesterol accumulation in macrophages leads to the formation of foam cells and
increases the risk of developing atherosclerosis. We have verified whether hydroxytyrosol …

[HTML][HTML] Quercetin increases macrophage cholesterol efflux to inhibit foam cell formation through activating PPARγ-ABCA1 pathway

L Sun, E Li, F Wang, T Wang, Z Qin… - International journal of …, 2015 - ncbi.nlm.nih.gov
The accumulation of cholesterol in macrophages could induce the formation of foam cells
and increase the risk of developing atherosclerosis. We wonder if quercetin, one of …

Vitamin E ameliorates ox-LDL-induced foam cells formation through modulating the activities of oxidative stress-induced NF-κB pathway

ZG Huang, C Liang, SF Han, ZG Wu - Molecular and Cellular Biochemistry, 2012 - Springer
The role of antioxidant supplementation with vitamin E in the prevention of atherosclerosis
has been a topic of considerable recent interest. The relevance of vitamin E for macrophage …

Bioactive components to inhibit foam cell formation in atherosclerosis

S Singh, S Changkija, R Mudgal… - Molecular Biology …, 2022 - Springer
Background The production of lipid-laden cells in macrophages after significant ingestion of
oxidized low-density lipoprotein is considered the most critical phase in the creation of …