Molecular quantification of residual disease in chronic myelogenous leukemia after bone marrow transplantation

JD Thompson, I Brodsky, JJ Yunis - 1992 - ashpublications.org
Residual disease remains a major problem in the treatment of human neoplasia. To
effectively monitor minimal leukemic activity after bone marrow transplantation (BMT), we …

Clinical significance of bcr-abl gene rearrangement detected by polymerase chain reaction after allogeneic bone marrow transplantation in chronic myelogenous …

R Delage, RJ Soiffer, K Dear, J Ritz - 1991 - ashpublications.org
In chronic myelogenous leukemia (CML), amplification of a segment of bcr-abl messenger
RNA (mRNA) by polymerase chain reaction (PCR) can be used to detect minimal residual …

Frequent detection of minimal residual disease by use of the polymerase chain reaction in long-term survivors after bone marrow transplantation for chronic myeloid …

JM Pignon, T Henni, S Amselem, M Vidaud… - Leukemia, 1990 - europepmc.org
The polymerase chain reaction (PCR) allows the detection of minimal amounts of nucleic
sequences and has been successfully used to test for the chronic myeloid leukemia-specific …

Simple competitive two-step RT-PCR assay to monitor minimal residual disease in CML patients after bone marrow transplantation

J Moravcova, M Lukášová, J Starý, C Haškovec - Leukemia, 1998 - nature.com
Quantitative reverse transcription-polymerase chain reaction (Q-RT-PCR) assessing the
amount of transcripts of the BCR/ABL gene, the molecular marker of chronic myeloid …

Molecular relapse in chronic myelogenous leukemia patients after bone marrow transplantation detected by polymerase chain reaction.

CL Sawyers, L Timson, ES Kawasaki… - Proceedings of the …, 1990 - National Acad Sciences
Relapse of chronic myelogenous leukemia after bone marrow transplantation can be
detected by using clinical, cytogenetic, or molecular tools. A modification of the polymerase …

Long persistent bcr-abl positive transcript detected by polymerase chain reaction after marrow transplant for chronic myelogenous leukemia without clinical relapse: a …

K Miyamura, T Tahara, M Tanimoto, Y Morishita… - 1993 - ashpublications.org
We report here the results of polymerase chain reaction (PCR) for bcr-abl transcript and
clinical details derived from 64 chronic myelogenous leukemia (CML) patients after …

Comparison of genomic DNA and cDNA for detection of residual disease after treatment of chronic myeloid leukemia with allogeneic bone marrow transplantation

JG Zhang, F Lin, A Chase, JM Goldman, NC Cross - 1996 - ashpublications.org
To test whether patients in remission after allogeneic bone marrow transplantation (BMT)
possess a pool of chronic myeloid leukemia (CML) cells that do not express BCR-ABL …

Polymerase chain reaction detection of the BCR-ABL fusion transcript after allogeneic marrow transplantation for chronic myeloid leukemia: results and implications in …

JP Radich, G Gehly, T Gooley, E Bryant, RA Clift… - 1995 - ashpublications.org
We studied 346 patients after bone marrow transplantation (BMT) for chronic myeloid
leukemia (CML) for the presence of the bcr-abl transcript detected by the polymerase chain …

Estimating the relapse stage in chronic myeloid leukaemia patients after allogeneic stem cell transplantation by the amount of BCR‐ABL fusion transcripts detected …

AH Elmaagacli, A Freist, M Hahn… - British journal of …, 2001 - Wiley Online Library
We have used a new single‐step real‐time reverse transcription polymerase chain reaction
(RT‐PCR) method to quantify BCR‐ABL transcripts, thereby estimating the relapse stage in …

Kinetics of increasing BCR-ABL transcript numbers in chronic myeloid leukemia patients who relapse after bone marrow transplantation

F Lin, F van Rhee, JM Goldman, NC Cross - 1996 - ashpublications.org
We prospectively studied 98 chronic myeloid leukemia (CML) patients after bone marrow
transplantation by competitive polymerase chain reaction to detect and quantify leukemia …