Delivery of free fatty acids to the liver in nonalcoholic fatty liver disease (NAFLD) may render
hepatocytes more vulnerable to glycochenodeoxycholic acid (GCDCA)-induced apoptosis …

Recent studies have identified a cholestatic variant of nonalcoholic fatty liver disease
(NAFLD) with portal inflammation and ductular reaction. Based on reports of biliary damage …

Fatty acid-induced lipotoxicity plays a critical role in the pathogenesis of nonalcoholic liver
disease. Saturated fatty acids and unsaturated fatty acids have differential effects on cell …

Background: Clinical studies have demonstrated improvement of parenteral nutrition (PN)–
associated liver disease (PNALD) with ω3 polyunsaturated fatty acid (ω3PUFA) …

Nonalcoholic steatohepatitis (NASH) patients have elevated plasma saturated free fatty acid
levels. These toxic fatty acids can induce liver cell death and our recent results …

Elevated serum free fatty acids (FFAs) and hepatocyte lipoapoptosis are features of non-
alcoholic fatty liver disease. However, the mechanism by which FFAs mediate lipoapoptosis …

Abstract Background and Aim: Studies have shown monounsaturated oleic acid to be less
toxic than palmitic acid and to prevent/attenuate palmitic acid hepatocites toxicity in steatosis …

Background Elevated serum saturated fatty acid levels and hepatocyte lipoapoptosis are
features of nonalcoholic fatty liver disease (NAFLD). Aim The purpose of this study was to …

Background/aims The accumulation of endogenous bile acids contributes to hepatocellular
damage during cholestatic liver disease. To evaluate the potential role of apoptotic cell …

Objectives Hepatic inflammation and degeneration induced by lipid depositions may be the
major cause of nonalcoholic fatty liver disease. In this study, we tried to investigate the …