The tools of functional genomics and proteomics have provided us with promising novel
biomarkers for acute kidney injury and chronic kidney disease. It will be important in future …

Acute kidney injury (AKI), previously referred to as acute renal failure, represents a common
and devastating problem in clinical medicine. Despite significant improvements in …

The current unidimensional paradigm of kidney disease detection is incompatible with the
complexity and heterogeneity of renal pathology. The diagnosis of kidney disease has …

Acute renal failure (ARF) as well as chronic kidney disease (CKD) are currently categorized
according to serum creatinine concentrations. Serum creatinine, however, has shortcomings …

The use of reliable biomarkers is becoming increasingly important for the improved
management of patients with acute and chronic kidney diseases. Recent developments …

The identification of acute kidney injury relies on tests like blood urea nitrogen and serum
creatinine that were identified and incorporated into clinical practice several decades ago …

Background: Acute kidney injury (AKI) is a major clinical problem with a rising incidence and
high mortality rate. The lack of early biomarkers has resulted in an unacceptable delay in …

Animal models and human studies have been useful in dissecting the molecular
mechanisms of renal disease and finding new disease targets; however, translation of these …

Proteomic biomarkers offer the hope of improving the management of patients with kidney
diseases by enabling more accurate and earlier detection of renal pathology than is …

New biomarkers of kidney injury and glomerular filtration rate hold the promise of
substantially improving the diagnostic approach to acute kidney injury. Adequately powered …