Direct oral anticoagulants versus warfarin in patients with atrial fibrillation: patient-level network meta-analyses of randomized clinical trials with interaction testing by …

AP Carnicelli, H Hong, SJ Connolly, J Eikelboom… - Circulation, 2022 - Am Heart Assoc
Background: Direct oral anticoagulants (DOACs) are preferred over warfarin for stroke
prevention in atrial fibrillation. Meta-analyses using individual patient data offer substantial …

[HTML][HTML] Oral anticoagulant underutilization among elderly patients with atrial fibrillation: insights from the United States Medicare database

MB Munir, P Hlavacek, A Keshishian, JD Guo… - Journal of Interventional …, 2023 - Springer
Abstract Background Oral anticoagulants (OACs) mitigate stroke risk in patients with atrial
fibrillation (AF). The study aim was to analyze prevalence and predictors of OAC …

Effectiveness and safety of off-label dose-reduced direct oral anticoagulants in atrial fibrillation

R Arbel, R Sergienko, A Hammerman… - The American Journal of …, 2019 - Elsevier
Abstract Background Direct oral anticoagulants (DOACs) reduce the risk of stroke and
systemic embolism in patients with nonvalvular atrial fibrillation but may result in serious …

[HTML][HTML] Current use of direct oral anticoagulants for atrial fibrillation in Japan: Findings from the SAKURA AF Registry

Y Okumura, K Yokoyama, N Matsumoto… - Journal of …, 2017 - Elsevier
Background Large-scale investigations on the use of oral anticoagulants including direct
oral anticoagulants (DOACs) in patients with atrial fibrillation (AF) have not included …

[HTML][HTML] Characteristics and outcomes in patients with atrial fibrillation receiving direct oral anticoagulants in off-label doses

A Briasoulis, Y Gao, C Inampudi, P Alvarez… - BMC cardiovascular …, 2020 - Springer
Background We evaluated adherence to dosing criteria for patients with atrial fibrillation (AF)
taking dabigatran or rivaroxaban and the impact of off-label dosing on thromboembolic and …

[HTML][HTML] Impact of polypharmacy and P-glycoprotein-and CYP3A4-modulating drugs on safety and efficacy of oral anticoagulation therapy in patients with atrial …

RE Harskamp, M Teichert, WAM Lucassen… - … drugs and therapy, 2019 - Springer
Purpose To study whether polypharmacy or drug–drug interactions have differential effect
on safety and efficacy in patients treated with direct oral anticoagulants (DOACs) versus …

[HTML][HTML] Inappropriate dosing of direct oral anticoagulants in patients with atrial fibrillation

K Lavoie, MH Turgeon, C Brais… - Journal of atrial …, 2016 - ncbi.nlm.nih.gov
Atrial fibrillation (AF) is a common cardiovascular disease for which newer oral
anticoagulants are available. The main objective of this study was to evaluate the …

Long-term risk of major adverse cardiac events in atrial fibrillation patients on direct oral anticoagulants

D Pastori, D Menichelli, F Del Sole, P Pignatelli… - Mayo Clinic …, 2021 - Elsevier
Objective To determine the association between direct oral anticoagulant (DOAC) use and
risk of major adverse cardiac events (MACEs) in patients with atrial fibrillation (AF). Patients …

[HTML][HTML] Effectiveness of direct oral anticoagulants in obese adults with atrial fibrillation: a systematic review of systematic reviews and meta-analysis

F Shaikh, R Wynne, RL Castelino, SC Inglis… - Frontiers in …, 2021 - frontiersin.org
Background: Atrial Fibrillation (AF) is the most common sustained cardiac arrhythmia.
Obesity is an independent risk factor for AF. Anticoagulants have been strongly …

Association between body mass index and clinical outcomes in patients with non-valvular atrial fibrillation receiving direct oral anticoagulants: a new piece of …

S Wu, N Huang, X Chen, S Jiang, W Zhang… - … Drugs and Therapy, 2023 - Springer
Purpose We conducted a multicenter real-world study in China to assess the association
between body mass index (BMI) and clinical outcomes in patients with atrial fibrillation (AF) …