Exploration of potential biomarkers and therapeutic targets for trauma-related acute kidney injury

P Qi, MJ Huang, W Wu, XW Ren, YZ Zhai… - Chinese Journal of …, 2024 - mednexus.org
Purpose: Acute kidney injury (AKI) is one of the most common functional injuries observed in
trauma patients. However, certain trauma medications may exacerbate renal injury …

[HTML][HTML] Identification and validation of potential biomarkers and their functions in acute kidney injury

J Chen, Y Chen, A Olivero, X Chen - Frontiers in Genetics, 2020 - frontiersin.org
Acute kidney injury (AKI) is a global public health concern associated with high morbidity,
mortality, and health-care costs, and the therapeutic measures are still limited. This study …

Identification of Hub Biomarkers and Inflammation-Related Pathways Participating in the Progression of AKI: FR-PO159

Q Chen, X Zhang, Z Xu, A Xu - Journal of the American Society of …, 2022 - journals.lww.com
Background: Acute kidney injury (AKI) is a common, potentially devastating condition
associated with markedly increased morbidity and mortality. We aim to identify key …

Comprehensive analysis of fifteen hub genes to identify a promising diagnostic model, regulated networks, and immune cell infiltration in acute kidney injury

T Sun, Y Cao, T Huang, Y Sang… - Journal of Clinical …, 2022 - Wiley Online Library
Background Acute kidney injury is a common clinical problem with no sensitive and specific
diagnostic biomarkers and definitive treatments. The underlying molecular mechanisms of …

Identification of novel prognostic targets in acute kidney injury using bioinformatics and next generation sequencing data analysis

BM Vastrad, CM Vastrad - bioRxiv, 2024 - biorxiv.org
Acute kidney injury (AKI) is a type of renal disease occurs frequently in hospitalized patients,
which may cause abnormal renal function and structure with increase in serum creatinine …

[HTML][HTML] Machine learning algorithm-based identification and verification of characteristic genes in acute kidney injury

Y Li, Y Du, Y Zhang, C Chen, J Zhang, X Zhang… - Frontiers in …, 2022 - frontiersin.org
Background Acute kidney injury is a common renal disease with high incidence and
mortality. Early identification of high-risk acute renal injury patients following renal transplant …

[HTML][HTML] Identification of multiple hub genes in acute kidney injury after kidney transplantation by bioinformatics analysis

SW Kang, SW Kang, JY Ban, MS Park - Medicina, 2022 - mdpi.com
Background and Objectives: The molecular mechanisms of the development of acute kidney
injury (AKI) after kidney transplantation are not yet clear. The aim of this study was to confirm …

[HTML][HTML] Data driven analysis reveals prognostic genes and immunological targets in human sepsis-associated acute kidney injury

Q Zhao, J Ma, J Xiao, Z Feng, H Liu - World Journal of Emergency …, 2024 - ncbi.nlm.nih.gov
BACKGROUND: The molecular mechanism of sepsis-associated acute kidney injury (SA-
AKI) is unclear. We analyzed co-differentially expressed genes (co-DEGs) to elucidate the …

[HTML][HTML] Comprehensive network-based analyses reveal novel renal function-related targets in acute kidney injury

Y Zhang, J Cai, W Lu, S Xu, M Qu, S Zhao… - Frontiers in …, 2022 - frontiersin.org
Background: Acute kidney injury (AKI) is a common clinical syndrome with limited methods
of treatment and diagnosis. Although several molecules associated with AKI have been …

[HTML][HTML] Identification of hub genes associated with acute kidney injury induced by renal ischemia–reperfusion injury in mice

S He, L He, F Yan, J Li, X Liao, M Ling, R Jing… - Frontiers in …, 2022 - frontiersin.org
Background: Acute kidney injury (AKI) is a severe clinical syndrome, and ischemia–
reperfusion injury is an important cause of acute kidney injury. The aim of the present study …