Hapten-specific, class II-restricted killing by cloned T cells: direct lysis and production of a cytotoxic factor.

JC Chang, JW Moorhead - Journal of immunology (Baltimore, Md …, 1986 - journals.aai.org
DNP-specific, class II-restricted cloned T cells were shown to kill DNP-bearing A20. 2J (A20-
DNP) antigen-presenting cells. This killing was DNP-specific and was restricted by IA …

Functional clonal deletion of class I-specific cytotoxic T lymphocytes by veto cells that express antigen.

HG Rammensee, PJ Fink, MJ Bevan - Journal of immunology …, 1984 - journals.aai.org
Intravenous injection of class I incompatible spleen cells into mice results in a drastic
reduction of the recipient's cytotoxic T lymphocyte (CTL) response against the injected, but …

Protein-antigen specific Ia-restricted cytolytic T cells: analysis of frequency, target cell susceptibility, and mechanism of cytolysis.

JP Tite, MB Powell, NH Ruddle - Journal of immunology (Baltimore …, 1985 - journals.aai.org
We previously showed that cloned, antigen-specific, Ia-restricted L3T4a+ T cell lines can be
cytolytic for antigen-pulsed B cell lymphoma targets. Such cells can also, under different …

Cloned cytolytic T cells can suppress primary cytotoxic responses directed against them.

PJ Fink, HG Rammensee, MJ Bevan - Journal of immunology …, 1984 - journals.aai.org
In vivo and in vitro, murine peripheral T cells can suppress or" veto" the activation of
cytotoxic T lymphocytes directed against antigens presented by those T cells. This …

Studies on the mechanism of suppression of primary cytotoxic responses by cloned cytotoxic T lymphocytes.

PJ Fink, HG Rammensee, JD Benedetto… - … (Baltimore, Md.: 1950 …, 1984 - journals.aai.org
We have shown in the accompanying companion paper that cloned cytotoxic T lymphocytes
(CTL) can serve as veto cells in vitro, suppressing primary cytotoxic activity directed against …

Mechanisms of lysis by cytotoxic T lymphocyte clones. Lytic activity and gene expression in cloned antigen-specific CD4+ and CD8+ T lymphocytes.

DW Lancki, CS Hsieh, FW Fitch - Journal of immunology (Baltimore …, 1991 - journals.aai.org
Cloned murine Th having properties of either Th1 or Th2 cells as well as CD8+ CTL were
tested for the capacity to lyse: 1) nucleated target cells bearing Ag or coated with anti-CD3 …

Studies on the Induction and Expression of T Cell-Mediated Immunity: I. Blocking of Cell-Mediated Cytolysis by Membrane Antigens

B Bonavida - The Journal of Immunology, 1974 - journals.aai.org
Serologically defined transplantation antigens from H-2b cells impaired the ability of immune
BALB/c (H-2d) thymus-derived (T) cells to mediate cytolysis of 51Cr-EL-4 cells. The blocking …

Lysis of allogeneic human lymphocytes by nonspecifically activated T‐like cells

AJ McMichael, FM Gotch… - European journal of …, 1982 - Wiley Online Library
In the generation of cytotoxic effector cells specific for influenza A virus‐infected
lymphocytes, three donors have given an unusual pattern of lytic activity, killing HLA …

Studies on the Induction and Expression of T Cell-Mediated Immunity: II. Antiserum Blocking of Cell-Mediated Cytolysis

B Bonavida - The Journal of Immunology, 1974 - journals.aai.org
Purified thymus-derived (T) cytotoxic lymphocytes were inhibited from mediating cytolysis of
51Cr-labeled target cells by alloantiserum directed against the target cell. Sensitization of …

Suppressor T cells, distinct from" veto cells," are induced by alloantigen priming and mediate transferable suppression of cytotoxic T lymphocyte responses in vivo.

T Owens, IN Crispe - Journal of immunology (Baltimore, Md.: 1950), 1985 - journals.aai.org
Primary and secondary cytotoxic T lymphocyte responses to minor alloantigens can be
suppressed by priming host mice with a high dose (10 (8) cells) of alloantigenic donor …