Despite the advent of numerous targeted therapies in clinical practice, anthracyclines,
including doxorubicin (DOX), continue to play a pivotal role in breast cancer (BC) treatment …

Due to its beneficial pharmacological properties, ferritin (Ftn) is considered as an interesting
drug delivery vehicle to alleviate the cardiotoxicity of doxorubicin (DOX) in chemotherapy …

Recently, drug delivery systems with tumor-targeting potential have been highly desirable
for improving the efficacy and applicability of drugs. With its cage structure, apoferritin (AFn) …

We report the development of a chemotherapeutic formulation made of polymeric-stabilized
multifunctional magnetic metal oxide nanoparticles (M3NPs) of ferrites loaded with the …

The purpose of this study was to construct and characterize iron oxide nanoparticles
(IONPCO) for intracellular delivery of the anthracycline doxorubicin (DOX; IONPDOX) in …

An ideal nanocarrier for efficient drug delivery must be able to target specific cells and carry
high doses of therapeutic drugs and should also exhibit optimized physicochemical …

Although immunotherapy of hepatocellular carcinoma using immune checkpoint inhibitors
has achieved certain success, only a subset of patients benefits from this therapeutic …

In metastatic breast cancer (MBC), the conventional doxorubicin (DOX) has various
problems due to lack of selectivity with subsequent therapeutic failure and adverse effects …

Chemotherapy is still regarded as the main modality for cancer treatment. However, it often
suppresses the host immune system, resulting in limited therapeutic effects. It is desirable to …

Triple negative breast cancer (TNBC) is difficult to treat effectively, due to its aggressiveness,
drug resistance, and lack of the receptors required for hormonal therapy, particularly at the …