[HTML][HTML] Bioactive nanotherapeutic trends to combat triple negative breast cancer

P Chowdhury, U Ghosh, K Samanta, M Jaggi… - Bioactive materials, 2021 - Elsevier
The management of aggressive breast cancer, particularly, triple negative breast cancer
(TNBC) remains a formidable challenge, despite treatment advancement. Although newer …

177Lu-Labeled Iron Oxide Nanoparticles Functionalized with Doxorubicin and Bevacizumab as Nanobrachytherapy Agents against Breast Cancer

EA Salvanou, A Kolokithas-Ntoukas, D Prokopiou… - Molecules, 2024 - mdpi.com
The use of conventional methods for the treatment of cancer, such as chemotherapy or
radiotherapy, and approaches such as brachytherapy in conjunction with the unique …

Therapeutic Potential of Methotrexate-Loaded Superparamagnetic Iron Oxide Nanoparticles Coated with Poly(lactic-co-glycolic acid) and Polyethylene Glycol against …

S Bhattacharya, BG Prajapati, N Ali, M Mohany… - ACS …, 2023 - ACS Publications
Novel superparamagnetic iron oxide nanoparticles (SPIONs) of Methotrexate (MTX) were
developed using supercritical liquid technology and optimized with a Box–Behnken design …

[HTML][HTML] GRP78-targeted ferritin nanocaged ultra-high dose of doxorubicin for hepatocellular carcinoma therapy

B Jiang, R Zhang, J Zhang, Y Hou, X Chen, M Zhou… - Theranostics, 2019 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) remains one of the leading causes of cancer deaths,
primarily due to its high incidence of recurrence and metastasis. Considerable efforts have …

[PDF][PDF] Dopamine-conjugated apoferritin protein nanocage for the dual-targeting delivery of epirubicin

HGJ Alqaraghuli, S Kashanian, R Rafipour… - Nanomed J, 2019 - researchgate.net
Objective (s): Nanocarriers are drug delivery vehicles, which have attracted the attention of
researchers in recent years, particularly in cancer treatment. The encapsulation of …

Exploring the Potential of Nanoparticles in the Treatment of Breast Cancer: Current Applications and Future Directions

P Patel, V Vedarethinam, MA Korsah, MK Danquah… - Applied Sciences, 2024 - mdpi.com
Featured Application This review explores an innovative approach to combating resistance
to breast cancer through the application of nanotechnology. Abstract Breast cancer (BC) …

Doxorubicin detoxification in healthy organs improves tolerability to high drug doses for enhanced antitumor therapy

Q Jiang, M Chen, X Yang, D Zhuge, Q Yin, D Tian… - ACS …, 2023 - ACS Publications
With its well-documented toxicity, the use of doxorubicin (Dox) for cancer treatment requires
trade-offs between safety and effectiveness. This limited use of Dox also hinders its …

Iron oxide nanoparticles for breast cancer theranostics

MS Shakil, MA Hasan, SR Sarker - Current drug metabolism, 2019 - ingentaconnect.com
Background: Breast cancer is the second leading cause of death in women worldwide. The
extremely fast rate of metastasis and ability to develop resistance mechanism to all the …

Furin-instructed aggregated gold nanoparticles for re-educating tumor associated macrophages and overcoming breast cancer chemoresistance

R Xie, S Ruan, J Liu, L Qin, C Yang, F Tong, T Lei… - Biomaterials, 2021 - Elsevier
Insufficient drug accumulation and chemoresistance remain two major challenges in cancer
chemotherapy. Herein, we designed a furin-responsive aggregated nanoplatform loaded …

Immobilized transferrin Fe3O4@SiO2 nanoparticle with high doxorubicin loading for dual-targeted tumor drug delivery

W Ding, L Guo - International journal of nanomedicine, 2013 - Taylor & Francis
Transferrin (Tf) was immobilized onto Fe3O4@ SiO2 nanoparticles with high doxorubicin
(DOX) loading (TfDMP), for dual targeting of cancer, by chemically coupling both Tf and DOX …