Sensitivity to cocaine conditioned reward depends on sex and age

E Zakharova, D Wade, S Izenwasser - Pharmacology Biochemistry and …, 2009 - Elsevier
Human and animal laboratory studies show that females and males respond differently to
drugs and that drug administration during adolescence leads to different behavioral effects …

Differential effects of methamphetamine and cocaine on conditioned place preference and locomotor activity in adult and adolescent male rats

E Zakharova, G Leoni, I Kichko, S Izenwasser - Behavioural brain research, 2009 - Elsevier
Human and animal laboratory studies show that adolescents and adults respond differently
to drugs and that drug administration during adolescence leads to different behavioral …

Sex differences in the conditioned rewarding effects of cocaine

SJ Russo, S Jenab, SJ Fabian, ED Festa, LM Kemen… - Brain research, 2003 - Elsevier
Several recent reports have demonstrated sex differences in the behavioral and
neurochemical response to cocaine. However, it is not clear whether differences exist in …

Influence of sex on reinstatement of cocaine-conditioned place preference

SAM Bobzean, TS Dennis, BD Addison, LI Perrotti - Brain research bulletin, 2010 - Elsevier
To explore sex differences in reinstatement of conditioned place preference, we subjected
intact male and female Long Evans rats to an extended conditioned place preference (CPP) …

Sex differences in cocaine conditioned place preference in C57BL/6J mice

ER Hilderbrand, AW Lasek - Neuroreport, 2014 - journals.lww.com
Men and women respond differently to the subjective effects of cocaine and cocaine-
associated cues, which has implications for the development and maintenance of cocaine …

Gonadal hormones differentially modulate cocaine-induced conditioned place preference in male and female rats

SJ Russo, ED Festa, SJ Fabian, FM Gazi, M Kraish… - Neuroscience, 2003 - Elsevier
There is accumulating evidence that suggests there are sex differences in behavioral and
subjective responses to cocaine. However, it is not known whether differences in cocaine …

Effects of periadolescent versus adult cocaine exposure on cocaine conditioned place preference and motor sensitization in mice

NL Schramm-Sapyta, AR Pratt, DG Winder - Psychopharmacology, 2004 - Springer
Rationale Age of initial exposure to addictive substances is inversely proportional to risk of
developing drug dependence. There is debate, however, as to whether intake at a young …

Conditioned place preference after single doses or “binge” cocaine in C57BL/6J and 129/J mice

Y Zhang, JR Mantsch, SD Schlussman, A Ho… - Pharmacology …, 2002 - Elsevier
The rewarding effect of cocaine as reflected by the development of conditioned place
preference was examined in C57BL/6J and 129/J mice. Cocaine was administered in a …

Cocaine and morphine-induced place conditioning in adolescent and adult rats

JO Campbell, RD Wood, LP Spear - Physiology & behavior, 2000 - Elsevier
The periadolescent period in the rat is characterized by alterations in novelty seeking and
exploratory behavior, as well as changes in the behavioral responsiveness to many drugs of …

Social and physical environment alter cocaine conditioned place preference and dopaminergic markers in adolescent male rats

E Zakharova, J Miller, E Unterwald, D Wade… - Neuroscience, 2009 - Elsevier
This study was done to determine whether social and environmental factors alter cocaine
reward and proteins implicated in mediating drug reward in rats during early adolescence …