A major concern in adolescent psychostimulant abuse is the long-term consequence of this
practice, because early drug exposure may cause long-term adaptations, which render the …

Recent rodent studies have demonstrated that parental cocaine exposure can influence
offspring behavior, supporting the idea that environmental insults can impact subsequent …

A great deal of research has focused on initiation into drug use and factors that increase the
risk of initiation or protect against it. Initiation into the use of some drugs (such as alcohol) is …

During a preexposure period rats were injected once daily with either cocaine HCl (10
mg/kg, IP) or the saline vehicle for 12 consecutive days. Rats that were chronically exposed …

Rationale Early-onset drug taking is associated with increased likelihood of addiction, but it
is unclear whether early onset is causal in development of addiction. Many other factors are …

The purpose of this study was to determine whether chronic exercise alters sensitivity to the
conditioned rewarding effects of cocaine. Female rats were obtained at weaning and …

Rationale The place conditioning procedure is increasingly used to study relapse in drug
seeking in mice. However, the retention course of drug-induced place preference has not …

Although more men than women are addicted to cocaine, it has been suggested that women
may have an accelerated transition to addiction, and that once addicted they may be more …

In this study, we measured conditioned place preference (CPP) responses to cocaine
following subchronic administration of the recreationally abused drug (±)‐3, 4 …

Adolescence is a transitional period during development that is associated with a greater
likelihood of addiction to drugs than any other age. One possibility for this observation is that …