The digitalis drugs are plant-derived cardenolide compounds used medicinally for several
hundred years. These drugs elicit inotropic and chronotropic effects on the heart, but they …

Digoxin metabolites cross-react in the Ciba Corning ACS digoxin assay in proportion to their
bioactivity, but have greater (near 100%) cross-reactivity in the Abbott TDx, Baxter Stratus …

Endogenous digoxin-like immunoreactive factors (DLIF) cross-react with antidigoxin
antibody and falsely elevate or lower measured serum digoxin concentrations, depending …

Digoxin is a cardioactive drug with a narrow therapeutic range. Therapeutic drug monitoring
is essential in clinical practice for efficacy as well as to avoid digoxin toxicity. Immunoassays …

We examined the specificity of three automated digoxin immunoassays (Abbott TDxFLx
Digoxin II assay, Baxter-Dade Stratus II Digoxin assay, and Ciba Corning ACS Digoxin …

Digoxin-like immunoreactive substance (DLIS) is known to interfere with fluorescence
polarization immunoassay (FPIA)(Digoxin II, Abbott Laboratories) and falsely elevates the …

Following digoxin Fab antibody (FAB) administration in digitalistoxic patients, total serum
digoxin concentrations (SDCS) become elevated, but do not correlate with pharmacologic …

In evaluating the EMIT (Syva Co.) digoxin assay, we found no cross reactivity between
dihydrodigoxin, the major digoxin metabolite, and the EMIT digoxin antibody from two …

Six commercial digoxin immunoassay kits were evaluated for their accuracy of calibration
and their extent of interference by digoxinlike immunoreactive substance (DLIS). Calibration …

This HPLC/immunoassay procedure measures digoxin in serum with no interference from
digoxin metabolites or digoxin-like factors. We used solid-phase (C18 and Diol) extraction, a …