[HTML][HTML] Therapeutic Implications of Renin–Angiotensin System Modulators in Alzheimer's Dementia
The Renin–Angiotensin System (RAS) has attracted considerable interest beyond its
traditional cardiovascular role due to emerging data indicating its potential involvement in …
traditional cardiovascular role due to emerging data indicating its potential involvement in …
Brain angiotensin II and angiotensin IV receptors as potential Alzheimer's disease therapeutic targets
J Royea, E Hamel - Geroscience, 2020 - Springer
Alzheimer's disease (AD) is a neurodegenerative disorder that is multifactorial in nature. Yet,
despite being the most common form of dementia in the elderly, AD's primary cause remains …
despite being the most common form of dementia in the elderly, AD's primary cause remains …
[HTML][HTML] Targeting renin–angiotensin system against Alzheimer's disease
Renin Angiotensin System (RAS) is a hormonal system that regulates blood pressure and
fluid balance through a coordinated action of renal, cardiovascular, and central nervous …
fluid balance through a coordinated action of renal, cardiovascular, and central nervous …
Renin-angiotensin system and Alzheimer's disease pathophysiology: from the potential interactions to therapeutic perspectives
VT Ribeiro, LC de Souza… - Protein and Peptide …, 2020 - ingentaconnect.com
New roles of the Renin-Angiotensin System (RAS), apart from fluid homeostasis and Blood
Pressure (BP) regulation, are being progressively unveiled, since the discoveries of RAS …
Pressure (BP) regulation, are being progressively unveiled, since the discoveries of RAS …
Current status of renin–aldosterone angiotensin system-targeting anti-hypertensive drugs as therapeutic options for Alzheimer's disease
EL Ashby, PG Kehoe - Expert opinion on investigational drugs, 2013 - Taylor & Francis
Introduction: Hypertension is a modifiable risk factor for Alzheimer's disease (AD) and other
dementias. Yet, despite this well-documented association, few of the current strategies to …
dementias. Yet, despite this well-documented association, few of the current strategies to …
The renin-angiotensin system and antihypertensive drugs in Alzheimer's disease: current standing of the angiotensin hypothesis?
PG Kehoe, PA Passmore - Journal of Alzheimer's Disease, 2012 - content.iospress.com
There is an urgent need to improve upon Alzheimer's disease (AD) treatments. Limitations of
existing drugs are that they target specific downstream neurochemical abnormalities while …
existing drugs are that they target specific downstream neurochemical abnormalities while …
[HTML][HTML] Targeting brain Renin-Angiotensin System for the prevention and treatment of Alzheimer's disease: Past, present and future
F Gouveia, A Camins, M Ettcheto, J Bicker… - Ageing Research …, 2022 - Elsevier
Alzheimer's disease (AD) is a well-known neurodegenerative disease characterized by the
presence of two main hallmarks–Tau hyperphosphorylation and Aβ deposits …
presence of two main hallmarks–Tau hyperphosphorylation and Aβ deposits …
The brain RAS and Alzheimer's disease
JW Wright, JW Harding - Experimental neurology, 2010 - Elsevier
Alzheimer's disease (AD) has become a major world-wide health problem with ever rising
costs associated with the treatment and care of afflicted individuals. As life expectancy has …
costs associated with the treatment and care of afflicted individuals. As life expectancy has …
Contributions by the brain renin-angiotensin system to memory, cognition, and Alzheimer's disease
JW Wright, JW Harding - Journal of Alzheimer's Disease, 2019 - content.iospress.com
Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive
neuron losses in memory-associated brain structures that rob patients of their dignity and …
neuron losses in memory-associated brain structures that rob patients of their dignity and …
Evidence to consider angiotensin II receptor blockers for the treatment of early Alzheimer's disease
JM Saavedra - Cellular and molecular neurobiology, 2016 - Springer
Alzheimer's disease is the most frequent type of dementia and diagnosed late in the
progression of the illness when irreversible brain tissue loss has already occurred. For this …
progression of the illness when irreversible brain tissue loss has already occurred. For this …