Mapping the iceberg of autonomic recovery: mechanistic underpinnings of neuromodulation following spinal cord injury

S Samejima, C Shackleton, T Miller… - The …, 2024 - journals.sagepub.com
Spinal cord injury leads to disruption in autonomic control resulting in cardiovascular, bowel,
and lower urinary tract dysfunctions, all of which significantly reduce health-related quality of …

The translational dialogue in spinal cord injury research

A Curt - Spinal cord, 2012 - nature.com
Background: Although the emphasis in clinical spinal cord injury (SCI) research has been
directed towards the evaluation of clinical assessments (standards in neurological …

Leveraging biomedical informatics for assessing plasticity and repair in primate spinal cord injury

JL Nielson, J Haefeli, EA Salegio, AW Liu… - Brain research, 2015 - Elsevier
Recent preclinical advances highlight the therapeutic potential of treatments aimed at
boosting regeneration and plasticity of spinal circuitry damaged by spinal cord injury (SCI) …

[HTML][HTML] The isolated sympathetic spinal cord: Cardiovascular and sudomotor assessment in spinal cord injury patients: A literature survey

JG Prévinaire, CJ Mathias, W El Masri, JM Soler… - Annals of physical and …, 2010 - Elsevier
OBJECTIVES: To present a comprehensive approach to the assessment of the severity of
the autonomic lesion in spinal cord injury (SCI) patients, with regard to the level of lesion. To …

Characterizing the temporal development of cardiovascular dysfunction in response to spinal cord injury

CR West, D Popok, MA Crawford… - Journal of …, 2015 - liebertpub.com
Spinal cord injury (SCI) is associated with rapid and sustained impairments in
cardiovascular function that ultimately cause an early onset of cardiovascular disease. We …

Functional testing in animal models of spinal cord injury: not as straight forward as one would think

K Fouad, C Hurd, DSK Magnuson - Frontiers in integrative …, 2013 - frontiersin.org
When exploring potential treatments for spinal cord injury (SCI), functional recovery is
deemed the most relevant outcome measure when it comes to translational considerations …

Relationship between severity of spinal cord injury and abnormalities in neurogenic cardiovascular control in conscious rats

DN MAIOROV, MG FEHLINGS… - Journal of …, 1998 - liebertpub.com
Abnormal sympathetic tone after spinal cord injury (SCI) initially results in hypotension and
is subsequently associated with autonomie dysreflexia characterized by paroxysmal …

Spinal electrical stimulation to improve sympathetic autonomic functions needed for movement and exercise after spinal cord injury: a scoping clinical review

S Flett, J Garcia, KC Cowley - Journal of Neurophysiology, 2022 - journals.physiology.org
Spinal cord injury (SCI) results in sensory, motor, and autonomic dysfunction. Obesity,
cardiovascular disease, and metabolic disease are highly prevalent after SCI. Although …

Autonomic dysreflexia in a mouse model of spinal cord injury

JE Jacob, A Pniak, LC Weaver, A Brown - Neuroscience, 2001 - Elsevier
Most experimental studies of spinal cord injury have centered on the rat as an experimental
model. A shift toward a mouse model has occurred in recent years because of its usefulness …

Cardiovascular dysfunction following spinal cord injury

E Partida, E Mironets, S Hou… - Neural regeneration …, 2016 - journals.lww.com
Both sensorimotor and autonomic dysfunctions often occur after spinal cord injury (SCI).
Particularly, a high thoracic or cervical SCI interrupts supraspinal vasomotor pathways and …