DNA methylation in insects: on the brink of the epigenomic era

KM Glastad, BG Hunt, SV Yi… - Insect molecular …, 2011 - Wiley Online Library
DNA methylation plays an important role in gene regulation in animals. However, the
evolution and function of DNA methylation has only recently emerged as the subject of …

Evolutionary insights into DNA methylation in insects

KM Glastad, BG Hunt, MAD Goodisman - Current Opinion in Insect Science, 2014 - Elsevier
Highlights•DNA methylation is an important epigenetic mark affecting gene
function.•Different insect species show great variation in levels of DNA methylation.•DNA …

Signatures of DNA methylation across insects suggest reduced DNA methylation levels in Holometabola

P Provataris, K Meusemann, O Niehuis… - Genome biology and …, 2018 - academic.oup.com
It has been experimentally shown that DNA methylation is involved in the regulation of gene
expression and the silencing of transposable element activity in eukaryotes. The variable …

The function of intragenic DNA methylation: insights from insect epigenomes

BG Hunt, KM Glastad, SV Yi… - Integrative and …, 2013 - academic.oup.com
Epigenetic inheritance plays a fundamentally important role in mediating gene regulation
and phenotypic plasticity. DNA methylation, in particular, has been the focus of many recent …

Evolution of DNA methylation across insects

AJ Bewick, KJ Vogel, AJ Moore… - Molecular biology and …, 2017 - academic.oup.com
DNA methylation contributes to gene and transcriptional regulation in eukaryotes, and
therefore has been hypothesized to facilitate the evolution of plastic traits such as sociality in …

[HTML][HTML] Widespread conservation and lineage-specific diversification of genome-wide DNA methylation patterns across arthropods

SH Lewis, L Ross, SA Bain, E Pahita, SA Smith… - PLoS …, 2020 - journals.plos.org
Cytosine methylation is an ancient epigenetic modification yet its function and extent within
genomes is highly variable across eukaryotes. In mammals, methylation controls …

Patterning and regulatory associations of DNA methylation are mirrored by histone modifications in insects

BG Hunt, KM Glastad, SV Yi… - Genome biology and …, 2013 - academic.oup.com
Epigenetic information is an important mediator of the relationship between genotype and
phenotype in eukaryotic organisms. One of the most important and widely conserved forms …

[HTML][HTML] Phenotypic plasticity: what has DNA methylation got to do with it?

EJ Duncan, CB Cunningham, PK Dearden - Insects, 2022 - mdpi.com
Simple Summary Phenotypic plasticity, the genome producing multiple phenotypes, is
central to an animal's ability to respond to environmental change, expected or otherwise. A …

Insects as innovative models for functional studies of DNA methylation

F Lyko, R Maleszka - Trends in genetics, 2011 - cell.com
The emerging field of epigenomics has the potential to bridge the gap between static
genomic sequences and complex phenotypes that arise from multigenic, nonlinear and …

DNA methylation in social insects: how epigenetics can control behavior and longevity

H Yan, R Bonasio, DF Simola, J Liebig… - Annual Review of …, 2015 - annualreviews.org
In eusocial insects, genetically identical individuals can exhibit striking differences in
behavior and longevity. The molecular basis of such phenotypic plasticity is of great interest …