Exosomes as immunotheranostic nanoparticles

G Natasha, B Gundogan, A Tan, Y Farhatnia, W Wu… - Clinical …, 2014 - Elsevier
Background Exosomes are small biological membrane vesicles that measure 30 to 100 nm
in diameter. They are involved in a wide array of biological activities, such as cell-cell …

The application of exosomes as a nanoscale cancer vaccine

A Tan, H De La Peña, AM Seifalian - International journal of …, 2010 - Taylor & Francis
Cancer is a leading cause of death globally, and it is predicted and projected to continue
rising as life expectancy increases. Although patient survival rates for some forms of cancers …

Designer exosomes as next-generation cancer immunotherapy

BM Bell, ID Kirk, S Hiltbrunner, S Gabrielsson… - … , Biology and Medicine, 2016 - Elsevier
Exosomes are small 40-120 nm vesicles secreted by nearly all cells and are an important
form of intercellular communication. Exosomes are abundant, stable, and highly …

Potential of cancer cell–derived exosomes in clinical application: a review of recent research advances

Y Sun, J Liu - Clinical therapeutics, 2014 - Elsevier
Abstract Background Exosomes are 30-to 100-nm, membrane-bound vesicles that are
released by most types of cells, including tumor cells. Exosomes contain a great variety of …

[HTML][HTML] Recent advances in exosome-based immunotherapy applied to cancer

J Xie, Z Zheng, L Tuo, X Deng, H Tang… - Frontiers in …, 2023 - frontiersin.org
Cancer stands as a prominent contributor to global mortality rates, necessitating immediate
attention toward the exploration of its treatment options. Extracellular vesicles have been …

Exosomes in diagnostic and therapeutic applications: biomarker, vaccine and RNA interference delivery vehicle

C Lässer - Expert opinion on biological therapy, 2015 - Taylor & Francis
Introduction: Cells release extracellular vesicles to their surroundings to communicate with
each other. Exosomes are a subgroup of 30–100-nm-sized extracellular vesicles, originating …

[HTML][HTML] Exosome-based immunotherapy: a promising approach for cancer treatment

Z Xu, S Zeng, Z Gong, Y Yan - Molecular cancer, 2020 - Springer
In the era of the rapid development of cancer immunotherapy, there is a high level of interest
in the application of cell-released small vesicles that stimulate the immune system. As cell …

Exosomes as a drug delivery tool for cancer therapy: A new era for existing drugs and oncolytic viruses

Y Kakiuchi, S Kuroda, N Kanaya… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Exosomes are cell-derived nanovesicles involved in cell-to-cell
communications. These nanovesicles are generally considered to contain important carriers …

[HTML][HTML] Potential application of exosomes in vaccine development and delivery

MN Huda, M Nurunnabi - Pharmaceutical Research, 2022 - Springer
Exosomes are cell-derived components composed of proteins, lipid, genetic information,
cytokines, and growth factors. They play a vital role in immune modulation, cell-cell …

[HTML][HTML] Exosomes: versatile nano mediators of immune regulation

Q Li, H Wang, H Peng, T Huyan, NA Cacalano - Cancers, 2019 - mdpi.com
One of many types of extracellular vesicles (EVs), exosomes are nanovesicle structures that
are released by almost all living cells that can perform a wide range of critical biological …