Posttraumatic epilepsy (PTE) is a recurrent seizure disorder that often develops secondary
to traumatic brain injury (TBI) that is caused by an external mechanical force. Recent …

Matrix metalloproteinases (MMP s) are a large family of proteases involved in many cell‐
matrix and cell‐cell signalling processes through activation, inactivation or release of …

Results of recent studies reveal vascular and neuroprotective effects of matrix
metalloproteinase-9 (MMP-9) inhibition and MMP-9 gene deletion in experimental stroke …

Abstract Matrix metalloproteinases (MMPs) are Zn 2+-dependent endopeptidases
considered to be essential for normal brain development and neuroplasticity by modulating …

Upregulation of matrix metalloproteinases (MMPs), especially MMP‐9, by oxidized low‐
density lipoprotein (oxLDL) is implicated in many inflammatory diseases including brain …

The blood–CSF barrier (BCSFB) consists of a monolayer of choroid plexus epithelial (CPE)
cells that maintain CNS homeostasis by producing CSF and restricting the passage of …

Background Numerous studies suggested that PM2. 5 exposure was associated with
increased risk of Alzheimer's disease (AD). But the precise mechanisms by which PM2. 5 …

Pathological changes in the Alzheimer's disease (AD) brain include amyoid-β (Aβ) plaques,
and neurofibrillary tangles, as well as neuronal death and synaptic loss. Matrix …

Neurofibrillary tangles and senile plaques, constituted of extracellular amyloid deposits (Aβ),
are the two defining pathological hallmarks of Alzheimer's disease (AD). Inhibiting the …

The immunoproteasome (iP), an inducible proteasome variant harboring three
immunosubunits, low molecular mass polypeptide-2 (LMP2), multicatalytic endopeptidase …