Psychotropic medications and the risk of fracture: a meta-analysis

B Takkouche, A Montes-Martinez, SS Gill, M Etminan - Drug safety, 2007 - Springer
Background: Older adults throughout the developed world are at significant risk of
osteoporotic fractures. Many studies have examined the relationship between the use of …

Fracture risk from psychotropic medications: a population-based analysis

JM Bolton, C Metge, L Lix, H Prior… - Journal of clinical …, 2008 - journals.lww.com
Background: Selective serotonin reuptake inhibitors (SSRIs), benzodiazepines, and
antipsychotics have each been associated with an increased risk of fracture in older …

Use of antipsychotics increases the risk of fracture: a systematic review and meta-analysis

SH Lee, WT Hsu, CC Lai, A Esmaily-Fard… - Osteoporosis …, 2017 - Springer
Our systematic review and meta-analysis of observational studies indicated that the use of
antipsychotics was associated with a nearly 1.5-fold increase in the risk of fracture. First …

Anxiolytics, sedatives, antidepressants, neuroleptics and the risk of fracture

P Vestergaard, L Rejnmark, L Mosekilde - Osteoporosis international, 2006 - Springer
Introduction: Our objective was to study the association between fracture risk and the use of
anxiolytics and sedatives (benzodiazepines, etc.), neuroleptics and antidepressants …

Antipsychotic use and the risk of hip/femur fracture: a population-based case–control study

S Pouwels, TP Van Staa, ACG Egberts… - Osteoporosis …, 2009 - Springer
This case–control study showed that current use of conventional antipsychotics, but not
atypical antipsychotics, seems to be associated with an increased risk of a hip/femur …

Psychotropic-related hip fractures: meta-analysis of first-generation and second-generation antidepressant and antipsychotic drugs

LH Oderda, JR Young, CV Asche… - Annals of …, 2012 - journals.sagepub.com
BACKGROUND: In 2007, more than 18,000 adults aged 65 or older died from injuries
related to falls, with up to 30% experiencing severe injuries such as hip fracture or head …

Risk of hip/femur fractures in patients using antipsychotics

GWK Hugenholtz, ER Heerdink, TP Van Staa… - Bone, 2005 - Elsevier
The objective of our study was to investigate whether use of antipsychotics is associated
with hip/femur fractures and whether pharmacological differences between antipsychotics …

Relationship between use of antidepressants and risk of fractures: a meta-analysis

V Rabenda, D Nicolet, C Beaudart, O Bruyère… - Osteoporosis …, 2013 - Springer
It has been shown that antidepressants would have a direct action on bone metabolism and
would be associated with increased fracture risk. Results from this large meta-analysis show …

Increased risk of hip fracture among older people using antidepressant drugs: data from the Norwegian Prescription Database and the Norwegian Hip Fracture …

MS Bakken, A Engeland, LB Engesæter… - Age and …, 2013 - academic.oup.com
Background: hip fractures are usually caused by a combination of reduced bone mineral
density and falls; using antidepressant drugs may affect both of these. Objective: we aimed …

Use of antidepressant drugs and risk of osteoporotic and non-osteoporotic fractures

BM Verdel, PC Souverein, TCG Egberts, TP Van Staa… - Bone, 2010 - Elsevier
AIM: Both tricyclic antidepressants (TCAs) and selective serotonin reuptake inhibitors
(SSRIs) have been associated with an increased risk of fractures. The serotonin transporter …