Context: The 46, XX male syndrome represents a rare, poorly characterized form of male
hypogonadism. Objective: The objective of the study was to distinguish the 46, XX male …

Abstract Context: Klinefelter syndrome (KS; 47, XXY karyotype and variants) is characterized
by tall stature and testicular failure, with marked variation in severity of the phenotype …

The condition of 46, XX maleness is characterized by testicular development in subjects who
have two X chromosomes but who lack a normal Y chromosome. Several etiologies have …

Klinefelter syndrome is characterized by progressive testicular failure causing androgen
deficiency and azoospermia in most patients. The aim of this study was to evaluate semen …

The main factor influencing the sex determination of an embryo is the genetic sex
determined by the presence or absence of the Y chromosome. However, some individuals …

Background To review the possible mechanisms proposed to explain the etiology of 46, XX
sex reversal by investigating the clinical characteristics and their relationships with …

Abstract Klinefelter (47, XXY) syndrome occurs in approximately 1: 800 male births and
accounts for about 10‐20% of males attending infertility clinics. Recent studies have shown …

OBJECTIVE Testicular differentiation can occur in the absence of the Y chromosome giving
XX sex‐reversed males. Although Y chromosomal sequences can be detected in the …

Objective To investigate how genetic features of the X chromosome influence growth,
pubertal development and testicular degeneration in adolescent boys with Klinefelter …

Abstract 47, XXY (Klinefelter syndrome) is the most frequent sex chromosomal disorder and
affects approximately one in 660 newborn boys. The syndrome is characterized by varying …