Recent efforts reclassified B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) into
more refined subtypes. Nevertheless, outcomes of relapsed BCP-ALL remain unsatisfactory …

B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is characterized by genetic
alterations with high heterogeneity. Precise subtypes with distinct genomic and/or gene …

Most B cell precursor acute lymphoblastic leukemia (BCP ALL) can be classified into known
major genetic subtypes, while a substantial proportion of BCP ALL remains poorly …

Transcriptome sequencing has identified multiple subtypes of B-progenitor acute
lymphoblastic leukemia (B-ALL) of prognostic significance, but a minority of cases lack a …

Genomic aberrations—gene fusions in the majority of cases—and corresponding
transcriptional regulations define an increasingly complex landscape of molecular subtypes …

B cell precursor acute lymphoblastic leukemia (BCP-ALL) is a blood cancer that originates
from the abnormal proliferation of B-lymphoid progenitors. Cell population components and …

Introduction The malignant transformation leading to a maturation arrest in B-cell precursor
acute lymphoblastic leukemia (BCP-ALL) occurs early in B-cell development, in a pro-B or …

Abstract Background Long non-coding RNAs (lncRNAs) have emerged as a novel class of
RNA due to its diverse mechanism in cancer development and progression. However, the …

RNA sequencing provides a snapshot of the functional consequences of genomic lesions
that drive acute lymphoblastic leukemia (ALL). The aims of this study were to elucidate …

Highlights•B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is currently treated by
risk-adapted intensive chemotherapy•Genome-wide genomic analyses have uncovered the …