Fatty acid binding proteins and the nervous system: Their impact on mental conditions

M Matsumata, H Inada, N Osumi - Neuroscience research, 2016 - Elsevier
The brain is rich in lipid and fatty molecules. In this review article, we focus on fatty acid
binding proteins (Fabps) that bind to fatty acids such as arachidonic acid and …

Emerging roles of lipid metabolism in cancer progression

C Corbet, O Feron - Current Opinion in Clinical Nutrition & …, 2017 - journals.lww.com
To proliferate, metastasize, or resist stress conditions imposed by the microenvironment,
many cancer cells rely on fatty acid β-oxidation to generate acetyl-CoA and fuel the TCA …

Increased rates of fatty acid uptake and plasmalemmal fatty acid transporters in obese Zucker rats

JJFP Luiken, Y Arumugam, DJ Dyck, RC Bell… - Journal of Biological …, 2001 - ASBMB
Giant vesicles were used to study the rates of uptake of long-chain fatty acids by heart,
skeletal muscle, and adipose tissue of obese and lean Zucker rats. With obesity there was …

Real-time quantification of fatty acid uptake using a novel fluorescence assay

J Liao, R Sportsman, J Harris, A Stahl - Journal of lipid research, 2005 - ASBMB
Uptake of nonesterified long-chain fatty acids (LCFAs) into many cell types and organs such
as liver, heart, intestine, and skeletal muscle occurs primarily through a saturable, protein …

The fatty acid transport function of fatty acid-binding proteins

J Storch, AEA Thumser - Biochimica et Biophysica Acta (BBA)-Molecular …, 2000 - Elsevier
The intracellular fatty acid-binding proteins (FABPs) comprise a family of 14–15 kDa proteins
which bind long-chain fatty acids. A role for FABPs in fatty acid transport has been …

Fatty acid signaling mechanisms in neural cells: fatty acid receptors

LJ Falomir-Lockhart, GF Cavazzutti… - Frontiers in cellular …, 2019 - frontiersin.org
Fatty acids (FAs) are typically associated with structural and metabolic roles, as they can be
stored as triglycerides, degraded by β-oxidation or used in phospholipids' synthesis, the …

Lipid metabolism in cancer progression and therapeutic strategies

Y Fu, T Zou, X Shen, PJ Nelson, J Li, C Wu, J Yang… - MedComm, 2021 - Wiley Online Library
Dysregulated lipid metabolism represents an important metabolic alteration in cancer. Fatty
acids, cholesterol, and phospholipid are the three most prevalent lipids that act as energy …

Lipids in the tumor microenvironment: From cancer progression to treatment

KC Corn, MKA Windham, M Rafat - Progress in lipid research, 2020 - Elsevier
Over the past decade, the study of metabolic abnormalities in cancer cells has risen
dramatically. Cancer cells can thrive in challenging environments, be it the hypoxic and …

Fatty acid transport proteins in disease: New insights from invertebrate models

P Dourlen, A Sujkowski, R Wessells… - Progress in lipid research, 2015 - Elsevier
The dysregulation of lipid metabolism has been implicated in various diseases, including
diabetes, cardiopathies, dermopathies, retinal and neurodegenerative diseases. Mouse …

Fatty acid metabolism in the progression and resolution of CNS disorders

JFJ Bogie, M Haidar, G Kooij, JJA Hendriks - Advanced drug delivery …, 2020 - Elsevier
Recent advances in lipidomics and metabolomics have unveiled the complexity of fatty acid
metabolism and the fatty acid lipidome in health and disease. A growing body of evidence …