Previously, large-scale proteomics was possible only for organisms whose genomes were
sequenced, meaning the most common model organisms. The use of next-generation …

Protein post-translational modifications (PTMs) play an important role in different cellular
processes. In view of the importance of PTMs in cellular functions and the massive data …

Post-translational modifications (PTMs) are involved in the regulation and structural
stabilization of eukaryotic proteins. The combination of individual PTM states is a key to …

The diversity of the cellular proteome substantially exceeds the number of genes coded by
the DNA of an organism because one or more residues in a majority of eukaryotic proteins …

Prokaryotic and eukaryotic microorganisms make a vital contribution to biogeochemical
cycles by decomposing virtually all natural compounds and thereby exert a lasting effect on …

The analysis of the post-translational modification (PTM) state of proteins using mass
spectrometry-based bottom-up proteomic workflows has evolved into a powerful tool for the …

The availability of complete genome sequences for a large number of pathogenic organisms
has opened the door for large‐scale proteomic studies to dissect both protein …

The number of protein isoforms in proteomes can be two to three orders of magnitude higher
than the number of genes in the genomes. This is in large part due to posttranslational …

Highlights•ABPP enabled proteomics and imaging provides insight into microbial
physiology.•Microbe functions, drug interactions, and pathways are revealed by …

With the rapid expansion of protein post-translational modification (PTM) research based on
large-scale proteomic work, there is an increasing demand for a suitable repository to …