A remarkable medical story: benefits of angiotensin-converting enzyme inhibitors in cardiac patients

ME Khalil, AW Basher, EJ Brown… - Journal of the American …, 2001 - jacc.org
The development of angiotensin-converting enzyme inhibitors (ACE inhibitors) has been
one of the most remarkable stories in the treatment of cardiovascular diseases. Angiotensin …

The anti‐ischemic potential of angiotensin‐converting enzyme inhibition: Insights from the Heart Outcomes Prevention Evaluation trial

B Pitt - Clinical Cardiology, 2000 - Wiley Online Library
Therapy with an angiotensin‐converting enzyme (ACE) inhibitor is established for reducing
excessive blood pressure, reducing mortality in patients with congestive heart failure (CHF) …

Emerging role of angiotensin-converting enzyme inhibitors in cardiac and vascular protection.

EM Lonn, S Yusuf, P Jha, TJ Montague, KK Teo… - Circulation, 1994 - Am Heart Assoc
A ngiotensin-converting enzyme (ACE) inhibitors are commonly used drugs in the
management of a variety of cardiovascular diseases. They are effective antihypertensive …

Angiotensin-converting enzyme inhibition in congestive heart failure: benefit and perspective

MA Pfeffer - American Heart Journal, 1993 - Elsevier
Therapy with angiotensin-converting enzyme (ACE) inhibitors was developed approximately
15 years ago as a novel therapeutic approach to hypertension. Although ACE inhibitor …

ACE inhibitors for patients with vascular disease without left ventricular dysfunction—may they rest in PEACE?

B Pitt - New England Journal of Medicine, 2004 - Mass Medical Soc
Angiotensin-converting–enzyme (ACE) inhibitors are effective in reducing mortality and
morbidity from cardiovascular events among patients who have chronic heart failure due to …

Angiotensin-converting enzyme inhibitors in coronary artery disease and preserved left ventricular systolic function: a systematic review and meta-analysis of …

MH Al-Mallah, IM Tleyjeh, AA Abdel-Latif… - Journal of the American …, 2006 - jacc.org
Objectives: This study sought to assess the efficacy of angiotensin-converting enzyme
inhibitors (ACEIs) in patients with coronary heart disease and preserved left ventricular (LV) …

Expanding the paradigm of the renin-angiotensin system and angiotensin-converting enzyme inhibitors

L Greenwald, RC Becker - American Heart Journal, 1994 - Elsevier
The renin-angiotensin system acts systemically and locally to influence vascular tone, blood
volume, myocardial contractility, thromboresistance, and tissue responses to injury. ACE …

Angiotensin-converting–enzyme inhibition in stable coronary artery disease

PEACE Trial Investigators - New England Journal of Medicine, 2004 - Mass Medical Soc
Background Angiotensin-converting–enzyme (ACE) inhibitors are effective in reducing the
risk of heart failure, myocardial infarction, and death from cardiovascular causes in patients …

Overview of randomized trials of angiotensin-converting enzyme inhibitors on mortality and morbidity in patients with heart failure

R Garg, S Yusuf, WD Bussmann, P Sleight, A Uprichard… - Jama, 1995 - jamanetwork.com
Objective.—To evaluate the effect of angiotensin-converting enzyme (ACE) inhibitors on
mortality and morbidity in patients with symptomatic congestive heart failure. Data Sources …

Are all angiotensin-converting enzyme inhibitors interchangeable?

CD Furberg, B Pitt - Journal of the American College of Cardiology, 2001 - jacc.org
In the treatment of most medical conditions, there are many choices. A critical question for
practicing clinicians is:“Are all drugs within a class interchangeable?” In the past decade, the …