Glucocorticoids are currently the most effective anti-inflammatory therapy for asthma.
However, a small subset of asthma sufferers do not respond to clinically relevant doses of …

Glucocorticoids are highly effective in the control of asthma and other chronic inflammatory
or immune diseases. The value of steroids in asthma became apparent soon after the …

Extensive development of inhaled and oral glucocorticoids has resulted in highly potent
molecules that have been optimized to target activity to the lung and minimize systemic …

Background: Glucocorticoid-resistant bronchial asthma is characterized by failure of
corticosteroids to suppress key asthma-relevant, cell–mediated inflammatory responses in …

Glucocorticosteroids are the first-line therapy for controlling airway inflammation in asthma.
They bind intracellular glucocorticoid receptors to trigger increased expression of anti …

Introduction: For decades glucocorticoids have been considered as the gold standard for the
treatment of asthma. We present a case report of typical glucocorticoid-resistant asthma and …

Inhaled glucocorticoids (GCs) are drugs widely used as treatment for asthma patients. They
prevent the recruitment and activation of lung immune and inflammatory cells and …

Glucocorticoids are the mainstay of asthma management and effectively treat acute
exacerbations of asthma. However, a small subset of asthmatics, usually with severe …

Bronchial asthma is assumed to be the result of excessive inflammation driven by an
aberrant T-helper-2 (Th2) response. Recently, it has begun to be recognized that asthma is …

Glucocorticoid insensitivity presents a profound management problem in patients with
asthma because conventional therapies are not effective. Glucocorticoids, acting through the …