[HTML][HTML] Multifunctional cationic host defence peptides and their clinical applications

ATY Yeung, SL Gellatly, REW Hancock - Cellular and Molecular Life …, 2011 - Springer
With the rapid rise in the emergence of bacterial strains resistant to multiple classes of
antimicrobial agents, there is an urgent need to develop novel antimicrobial therapies to …

[HTML][HTML] Antimicrobial peptides as anti-infective agents in pre-post-antibiotic era?

T Rončević, J Puizina, A Tossi - International journal of molecular …, 2019 - mdpi.com
Resistance to antibiotics is one of the main current threats to human health and every year
multi-drug resistant bacteria are infecting millions of people worldwide, with many dying as a …

[HTML][HTML] Expression and function of host defense peptides at inflammation sites

SV Prasad, K Fiedoruk, T Daniluk, E Piktel… - International journal of …, 2019 - mdpi.com
There is a growing interest in the complex role of host defense peptides (HDPs) in the
pathophysiology of several immune-mediated inflammatory diseases. The physicochemical …

Emerging themes and therapeutic prospects for anti-infective peptides

NY Yount, MR Yeaman - Annual review of pharmacology and …, 2012 - annualreviews.org
Pathogens resistant to most conventional anti-infectives are a harbinger of the need to
discover and develop novel anti-infective agents and strategies. Endogenous host defense …

[HTML][HTML] Towards robust delivery of antimicrobial peptides to combat bacterial resistance

M Drayton, JN Kizhakkedathu, SK Straus - Molecules, 2020 - mdpi.com
Antimicrobial peptides (AMPs), otherwise known as host defence peptides (HDPs), are
naturally occurring biomolecules expressed by a large array of species across the …

Membrane‐active small molecules: designs inspired by antimicrobial peptides

C Ghosh, J Haldar - ChemMedChem, 2015 - Wiley Online Library
Infectious diseases continue to be one of the major contributors to human morbidity. The
rapid rate at which pathogenic microorganisms have developed resistance against frontline …

[HTML][HTML] Antimicrobial peptides: an emerging category of therapeutic agents

M Mahlapuu, J Håkansson, L Ringstad… - Frontiers in cellular and …, 2016 - frontiersin.org
Antimicrobial peptides (AMPs), also known as host defense peptides, are short and
generally positively charged peptides found in a wide variety of life forms from …

[图书][B] Antimicrobial peptides: discovery, design and novel therapeutic strategies

WGS Wang GuangShun - 2017 - cabidigitallibrary.org
Antimicrobial peptides (AMPs) have attracted extensive research attention worldwide.
Harnessing and creating AMPs synthetically has the potential to help overcome increasing …

Antimicrobial peptides and macromolecules for combating microbial infections: from agents to interfaces

L Yu, K Li, J Zhang, H Jin, A Saleem… - ACS Applied Bio …, 2022 - ACS Publications
Bacterial resistance caused by the overuse of antibiotics and the shelter of biofilms has
evolved into a global health crisis, which drives researchers to continuously explore …

[HTML][HTML] Host defense peptides as effector molecules of the innate immune response: a sledgehammer for drug resistance?

L Steinstraesser, UM Kraneburg, T Hirsch… - International journal of …, 2009 - mdpi.com
Host defense peptides can modulate the innate immune response and boost infection-
resolving immunity, while dampening potentially harmful pro-inflammatory (septic) …