Roles of d-Amino Acids on the Bioactivity of Host Defense Peptides
H Li, N Anuwongcharoen, AA Malik… - International journal of …, 2016 - mdpi.com
Host defense peptides (HDPs) are positively-charged and amphipathic components of the
innate immune system that have demonstrated great potential to become the next …
innate immune system that have demonstrated great potential to become the next …
Cationic host defence peptides: innate immune regulatory peptides as a novel approach for treating infections
N Mookherjee, REW Hancock - Cellular and molecular life sciences, 2007 - Springer
An increase in antibiotic resistance and the emergence of new pathogens has led to an
urgent need for alternative approaches to infection management. Immunomodulatory …
urgent need for alternative approaches to infection management. Immunomodulatory …
Post-translational modifications of natural antimicrobial peptides and strategies for peptide engineering
G Wang - Current biotechnology, 2012 - ingentaconnect.com
Natural antimicrobial peptides (AMPs) are gene-coded defense molecules discovered in all
the three life domains: Eubacteria, Archaea, and Eukarya. The latter covers protists, fungi …
the three life domains: Eubacteria, Archaea, and Eukarya. The latter covers protists, fungi …
Cationic amphiphiles, a new generation of antimicrobials inspired by the natural antimicrobial peptide scaffold
B Findlay, GG Zhanel, F Schweizer - Antimicrobial agents and …, 2010 - Am Soc Microbiol
Naturally occurring cationic antimicrobial peptides (AMPs) and their mimics form a diverse
class of antibacterial agents currently validated in preclinical and clinical settings for the …
class of antibacterial agents currently validated in preclinical and clinical settings for the …
Combination effects of antimicrobial peptides
Antimicrobial peptides (AMPs) are ancient and conserved across the tree of life. Their
efficacy over evolutionary time has been largely attributed to their mechanisms of killing. Yet …
efficacy over evolutionary time has been largely attributed to their mechanisms of killing. Yet …
Synthetic cationic amphiphilic α-helical peptides as antimicrobial agents
N Wiradharma, U Khoe, CAE Hauser, SV Seow… - Biomaterials, 2011 - Elsevier
Antimicrobial peptides (AMPs) secreted by the innate immune system are prevalent as the
effective first-line of defense to overcome recurring microbial invasions. They have been …
effective first-line of defense to overcome recurring microbial invasions. They have been …
Perspectives for clinical use of engineered human host defense antimicrobial peptides
Infectious diseases caused by bacteria, viruses or fungi are among the leading causes of
death worldwide. The emergence of drug-resistance mechanisms, especially among …
death worldwide. The emergence of drug-resistance mechanisms, especially among …
Antimicrobial peptides: natural effectors of the innate immune system
K Radek, R Gallo - Seminars in immunopathology, 2007 - Springer
Antimicrobial peptides (AMPs) are an evolutionarily conserved component of the innate
immune system that defend against invading bacteria, viruses, and fungi through membrane …
immune system that defend against invading bacteria, viruses, and fungi through membrane …
Antimicrobial peptides: key components of the innate immune system
M Pasupuleti, A Schmidtchen… - Critical reviews in …, 2012 - Taylor & Francis
Life-threatening infectious diseases are on their way to cause a worldwide crisis, as treating
them effectively is becoming increasingly difficult due to the emergence of antibiotic resistant …
them effectively is becoming increasingly difficult due to the emergence of antibiotic resistant …
A new era of antibiotics: the clinical potential of antimicrobial peptides
Antimicrobial resistance is a multifaceted crisis, imposing a serious threat to global health.
The traditional antibiotic pipeline has been exhausted, prompting research into alternate …
The traditional antibiotic pipeline has been exhausted, prompting research into alternate …