Amelioration of gut dysbiosis and gastrointestinal motility by konjac oligo-glucomannan on loperamide-induced constipation in mice

F Hayeeawaema, S Wichienchot, P Khuituan - Nutrition, 2020 - Elsevier
Objective Konjac oligo-glucomannan (KOG) is a non-digestible dietary fiber that is resistant
to digestion and absorption in gastrointestinal (GI) tract. Thus, it might be used as an …

Prevention of loperamide induced constipation in mice by KGM and the mechanisms of different gastrointestinal tract microbiota regulation

Q Zhang, D Zhong, R Sun, Y Zhang, RB Pegg… - Carbohydrate …, 2021 - Elsevier
Constipation is one of the most prevalent gastrointestinal tract diseases. Konjac
glucomannan (KGM) dietotherapy can effectively relieve the clinical symptoms of patients …

Konjac glucomannan with probiotics acts as a combination laxative to relieve constipation in mice by increasing short-chain fatty acid metabolism and 5 …

Y Lu, J Zhang, Z Zhang, X Liang, T Liu, H Yi, P Gong… - Nutrition, 2021 - Elsevier
Objectives Various probiotics and natural products can help to relieve constipation. This
study aimed to explore the constipation-relieving effects and potential mechanism of a …

Comparative study of the laxative effects of konjac oligosaccharides and konjac glucomannan on loperamide-induced constipation in rats

M Hu, C Fang, Y Liu, M Gao, D Zhang, G Shi, Z Yin… - Food & Function, 2021 - pubs.rsc.org
Dietary fiber is the basic therapeutic method to relieve the symptoms of chronic constipation.
The aim of this study was to compare the laxative effect of konjac glucomannan (KGM) and …

Effect of konjac glucomannan on metabolites in the stomach, small intestine and large intestine of constipated mice and prediction of the KEGG pathway

Q Zhang, D Zhong, YY Ren, Z Meng, RB Pegg… - Food & Function, 2021 - pubs.rsc.org
The occurrence of constipation involves the whole gastrointestinal tract. Konjac
glucomannan (KGM) has been clinically proven to alleviate constipation, but its mechanism …

Konjac acts as a natural laxative by increasing stool bulk and improving colonic ecology in healthy adults

HL Chen, HC Cheng, YJ Liu, SY Liu, WT Wu - Nutrition, 2006 - Elsevier
OBJECTIVE: Konjac glucomannan (KGM) has been shown to relieve constipation, which
could be associated with increased stool bulk and improved colonic ecology. METHODS …

Comparative effects of different enzymatic hydrolysates of konjac glucomannan on gut flora and constipation in rats

X Chang, Y Liu, M Hu, Y Liu, C Jiang, Q Wang, Q Jin… - Food & Function, 2022 - pubs.rsc.org
This study aimed to compare the effects of different hydrolysates (named GKOS and MKOS)
on constipated rats, which were obtained by degradation from konjac glucomannan by β …

Effect of Konjac mannan oligosaccharides on diphenoxylate-induced constipation in mice

X Liu, S Chen, Q Yan, Y Li, Z Jiang - Journal of Functional Foods, 2019 - Elsevier
The effects of Konjac mannan oligosaccharides (KMOS) on diphenoxylate-induced
constipation in mice were investigated in the present study. After administration with KMOS …

Comparison of the laxative effects of Korean Gochujang containing different microbiota on loperamide-induced constipation in ICR mice

NY Kim, KA Kim, HJ Yang, SJ Jeong, A Han… - Food & Function, 2023 - pubs.rsc.org
The prevalence of constipation, one of the common gastrointestinal (GI) diseases, has been
gradually increasing. Gochujang, a traditional Korean fermented paste, has various …

Supplementation of konjac glucomannan into a low-fiber Chinese diet promoted bowel movement and improved colonic ecology in constipated adults: a placebo …

HL Chen, HC Cheng, WT Wu, YJ Liu… - Journal of the American …, 2008 - Taylor & Francis
Objectives: This diet-controlled study was designed to examine effects of konjac
glucomannan (KGM) supplement on the bowel habits and colonic ecology in 7 constipated …